13 Papers
1 Citations
Ian Baine is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Antibody & Seroconversion. The author has an hindex of 10, co-authored 13 publications.
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Papers
Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study.
Sean T. H. Liu,Hung-Mo Lin,Ian Baine,Ania Wajnberg,Jeffrey P. Gumprecht,Farah Rahman,Denise Rodriguez,Pranai Tandon,Adel Bassily-Marcus,Jeffrey Bander,Charles Sanky,Amy C. Dupper,Allen Zheng,Freddy T. Nguyen,Fatima Amanat,Daniel Stadlbauer,Deena R. Altman,Benjamin K. Chen,Florian Krammer,Damodara Rao Mendu,Adolfo Firpo-Betancourt,Matthew A. Levin,Emilia Bagiella,Arturo Casadevall,Carlos Cordon-Cardo,Jeffrey S. Jhang,Suzanne Arinsburg,David Reich,Judith A. Aberg,Nicole M. Bouvier +29 more
TL;DR: Convalescent plasma is potentially effective against COVID-19, but adequately powered, randomized controlled trials are needed.
Humoral response and PCR positivity in patients with COVID-19 in the New York City region, USA: an observational study.
Ania Wajnberg,Mayce Mansour,Emily Leven,Nicole M. Bouvier,Gopi Patel,Adolfo Firpo-Betancourt,Rao Mendu,Jeffrey S. Jhang,Suzanne Arinsburg,Melissa R. Gitman,Jane Houldsworth,Emilia Mia Sordillo,Alberto Paniz-Mondolfi,Ian Baine,Viviana Simon,Judith A. Aberg,Florian Krammer,David Reich,Carlos Cordon-Cardo +18 more
- 25 Sep 2020
TL;DR: Analysis of a large cohort of convalescent serum donors in the New York City region suggests that most patients with mild COVID-19 seroconvert 4 weeks after illness, and raises questions about the use of PCR to clear positive individuals.
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Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera.
Kasopefoluwa Y. Oguntuyo,Christian S. Stevens,Chuan Tien Hung,Satoshi Ikegame,Joshua A. Acklin,Shreyas Kowdle,Jillian C. Carmichael,Hsin-Ping Chiu,Kristopher D. Azarm,Griffin Haas,Fatima Amanat,Jéromine Klingler,Jéromine Klingler,Ian Baine,Suzanne Arinsburg,Juan C. Bandres,Juan C. Bandres,Mohammed N. A. Siddiquey,Robert M Schilke,Matthew D. Woolard,Hongbo Zhang,Andrew J. Duty,Thomas Kraus,Thomas M. Moran,Domenico Tortorella,Jean K. Lim,Andrea V. Gamarnik,Catarina E. Hioe,Catarina E. Hioe,Susan Zolla-Pazner,Stanimir S. Ivanov,Jeremy P. Kamil,Florian Krammer,Benhur Lee +33 more
TL;DR: The CoV2pp-VNA as mentioned in this paper is based on vesicular stomatitis virus bearing the Renilla luciferase gene in place of its G glycoprotein (VSVΔG), which can be robustly produced at scale and generate accurate neutralizing titers within 18 h postinfection.
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Role of Immunoglobulin M and A Antibodies in the Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2.
Jéromine Klingler,Jéromine Klingler,Svenja Weiss,Svenja Weiss,Vincenza Itri,Xiaomei Liu,Xiaomei Liu,Kasopefoluwa Y. Oguntuyo,Christian S. Stevens,Satoshi Ikegame,Chuan-Tien Hung,Gospel Enyindah-Asonye,Fatima Amanat,Ian Baine,Suzanne Arinsburg,Juan C. Bandres,Erna Milunka Kojic,Jonathan Stoever,Denise Jurczyszak,Maria Bermudez-Gonzalez,Arthur Nádas,Sean T. H. Liu,Benhur Lee,Susan Zolla-Pazner,Catarina E. Hioe,Catarina E. Hioe +25 more
TL;DR: In this article, the authors studied spike and RBD-specific immunoglobulin isotypes in convalescent and acute plasma/serum samples using a multiplex bead assay.
A High-Throughput Assay for Circulating Antibodies Directed Against the S Protein of Severe Acute Respiratory Syndrome Coronavirus 2.
Svenja Weiss,Jéromine Klingler,Catarina E. Hioe,Catarina E. Hioe,Fatima Amanat,Ian Baine,Suzanne Arinsburg,Erna Milunka Kojic,Jonathan Stoever,Sean T. H. Liu,Denise Jurczyszak,Maria Bermudez-Gonzalez,Viviana Simon,Florian Krammer,Susan Zolla-Pazner +14 more
TL;DR: A Luminex binding assay was developed and used to assess simultaneously the presence of coronavirus disease 2019 (COVID-19)–specific antibodies in human serum and plasma, and clear differentiation was achieved between specimens from infected and uninfected subjects, and a wide range of serum/plasma antibody levels was delineated in infected subjects.
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