5 Papers
I Sim is an academic researcher from King's College London. The author has contributed to research in topics: Atrial fibrillation & Medicine. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of I Sim include St Thomas' Hospital.
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Papers
Left atrial voltage mapping: defining and targeting the atrial fibrillation substrate.
TL;DR: Clinical evidence with regard to voltage-based ablation procedures is reviewed and omnipole mapping and dynamic voltage attenuation are discussed as two possible approaches to resolving issues.
Quantifying Atrial Anatomy Uncertainty from Clinical Data and its Impact on Electro-physiology Simulation Predictions
Cesare Corrado,Orod Razeghi,Caroline H. Roney,Sam Coveney,Steven Williams,I Sim,Mark D O'Neill,Richard D. Wilkinson,Jeremy E. Oakley,Richard H. Clayton,Steven A. Niederer +10 more
TL;DR: This work uses a Bayesian probabilistic approach to estimate the anatomy and to quantify the uncertainty about the shape of the left atrium derived from Cardiac Magnetic Resonance images, and quantifies the effect of uncertain shape on simulations of left atrial activation times.
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4 Characterisation of the structural and electrical impact of an atrial septal defect: CMR evaluation of the arrhythmia substrate
L O’Neill,Steven Williams,Orod Razeghi,John Whitaker,I Sim,Rahul K Mukherjee,S Niederer,Matthew Wright,H Alam,A Frigiola,Mark D O'Neill +10 more
TL;DR: Right atrial fibrosis is present in ASD patients to a significantly greater degree than left atrian fibrosis and the relationship between RA and presence of AAs is investigated.
Pulmonary vein encirclement using an Ablation Index-guided point-by-point workflow: cardiovascular magnetic resonance assessment of left atrial scar formation.
Louisa O'Neill,Rashed Karim,Rahul K Mukherjee,John Whitaker,John Whitaker,I Sim,James Harrison,Orod Razeghi,Steven A. Niederer,Tevfik F Ismail,Tevfik F Ismail,Matthew Wright,Mark D O'Neill,Mark D O'Neill,Steven Williams,Steven Williams +15 more
TL;DR: Pulmonary vein isolation using a point-by-point workflow is feasible and results in a lower scar burden and scar width with more complete pulmonary vein encirclements than a conventional drag lesion approach.
Left atrial effective conducting size predicts atrial fibrillation vulnerability in persistent but not paroxysmal atrial fibrillation.
Steven Williams,Louisa O'Neill,Caroline H. Roney,Justo Juliá,Andreas Metzner,Bruno Reißmann,Rahul K Mukherjee,I Sim,John Whitaker,Matthew Wright,Steven A. Niederer,Christian Sohns,Mark D O'Neill +12 more
TL;DR: This work investigated the relationship between left atrial effective conducting size (LAECS), a function of area, CV and refractoriness, and AF vulnerability in patients undergoing AF ablation.