I.O. Szymanski
University of Massachusetts Amherst
46 Papers
509 Citations
I.O. Szymanski is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Rh blood group system & Agglutination (biology). The author has an hindex of 16, co-authored 46 publications. Previous affiliations of I.O. Szymanski include St. Vincent's Health System & Boston Children's Hospital.
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Papers
Hematologic changes during and after cardiopulmonary bypass and their relationship to the bleeding time and nonsurgical blood loss.
Shukri F. Khuri,J. Alan Wolfe,Miguel Josa,Trevor C. Axford,I.O. Szymanski,Samar N. Assousa,Gina Ragno,Manisha A. Patel,Andrew B. Silverman,Michael Park,C. Robert Valeri +10 more
TL;DR: Data indicate that the reversal of the postoperative extension of the bleeding time is due in part to rewarming and to the release of larger platelets into the circulation, and they suggest that hyperfibrinolysis and complement activation may play an important role in the cardiopulmonary bypass-induced platelet dysfunction.
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Epstein-barr virus infections in the x-linked recessive lymphoproliferative syndrome
DavidT. Purtilo,Jag Bhawan,LindseyM. Hutt,Lucian K. Denicola,I.O. Szymanski,JamesP.S. Yang,William Boto,Rorert Maier,David A. Thorley-Lawson +8 more
TL;DR: Variable phenotypic expression of the X-linked recessive lymphoproliferative syndrome probably resulted from the varied immune response to E.B.V, which can induce fatal I.R.M. and malignant lymphoma in X.L.S., but an immune responseto E.V. can be protective.
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Red blood cell associated IgG in normal and pathologic states
I.O. Szymanski,I.O. Szymanski,Paul R. Odgren,Paul R. Odgren,NL Fortier,NL Fortier,LM Snyder,LM Snyder +7 more
TL;DR: The degree of anti-IgG-induced RBC agglutination correlated negatively with the reticulocyte count and positively with the concentration of plasma IgG, suggesting that immunoglobulin G accumulated gradually on the RBC membrane in vivo.
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Red cell membrane response to hydrogen peroxide-sensitivity in hereditary xerocytosis and in other abnormal red cells.
TL;DR: Osmotically resistant red cells associated with some haemolytic anaemias are more sensitive than normal red cells to exogenous in vitro hydrogen peroxide, and membrane protein cross‐linking occurring immediately following H2O2 exposure seems independent of either the sulfhydryl or MDA mechanisms.
47
Increased Apoptosis of CD20+ IgA+ B Cells is the Basis for IgA Deficiency: The Molecular Mechanism for Correction In Vitro by IL-10 and CD40L
TL;DR: In CD19+ B cells from IgAd donors, reconstitution of IgA secretion was associated with protection of the CD20+ B cell population that underwent apoptosis in the absence of IL-10, CD40L, and TT (triple treatment).
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