I-Ning E. Wang
Stanford University
5 Papers
19 Citations
I-Ning E. Wang is an academic researcher from Stanford University. The author has contributed to research in topics: Transplantation & Embryoid body. The author has an hindex of 4, co-authored 5 publications.
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Papers
Graphite Oxide Nanoparticles with Diameter Greater than 20 nm Are Biocompatible with Mouse Embryonic Stem Cells and Can Be Used in a Tissue Engineering System
I-Ning E. Wang,Joshua T. Robinson,Grace Do,Guosong Hong,Danny R. Gould,Hongjie Dai,Phillip C. Yang +6 more
TL;DR: The selection criteria for a biomaterial candidate include the following: biocompatibility with ESCs without affecting their pluripotency, survival, or proliferation; nano-scale to be deliverable with the cells; and cross-link or bind to hydrophobic biomolecules such as pro-survival molecules or extracellular matrix molecules to facilitate engraftment.
Manganese-enhanced MRI detects live human amnion-derived mesenchymal stem cells in vivo after transplantation and restoration of myocardial function in a pig ischemia-reperfusion injury model
Rajesh Dash,Ildiko Toma,Fumiaki Ikeno,Jennifer Lyons,Shahriar Heidary,Marie-Claude Parent,I-Ning E. Wang,Xiaohu Ge,Jaehoon Chung,Justin Lam,Paul J Kim,Kaori Nakagawa,Svetlana Lyalina,Grace Do,Robert C. Robbins,Michael V. McConnell,Alan C. Yeung,Phillip Harnish,Phillip C. Yang +18 more
TL;DR: Human Amnion-derived Mesenchymal Stem Cells were transplanted into the infarct and periinfarct regions of a pig ischemia-reperfusion model and improved cardiac systolic function post-MI, and Cardiac MRI with Manganese-Enhanced MRI was able to detect increased CNR from live populations of hAMSCs.
Manganese-enhanced MRI in the evaluation of cell-based therapy for myocardial restoration
TL;DR: A trend towards improved LVEF with ESC-RGs transplanted hearts, consistent with the results of this group’s previously published data, may support the hypothesis that functional improvement with stem cell therapy may be due to myocardial salvage.
Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells.
I-Ning E. Wang,Xiang Wang,Xiaohu Ge,Joshua P. Anderson,Michael Ho,Euan A. Ashley,Jianwei Liu,Manish J. Butte,Masayuki Yazawa,Ricardo E. Dolmetsch,Thomas Quertermous,Phillip C. Yang +11 more
TL;DR: It is demonstrated that the treatment of apelin enhanced cardiac differentiation of mouse and human ESCs and exhibited synergistic effects with mesodermal differentiation factors.
Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells.
Xiaohu Ge,I-Ning E. Wang,Ildiko Toma,Vittorio Sebastiano,Jianwei Liu,Manish J. Butte,Renee A. Reijo Pera,Phillip C. Yang +7 more
TL;DR: It is demonstrated that the hAMSCs are reprogrammed with a high efficiency into MiPSCs, which possess pluripotent, immunomodulatory, and precardiac properties.