I. Mulas
6 Papers
I. Mulas is an academic researcher. The author has contributed to research in topics: Niche & Paracrine signalling. The author has an hindex of 1, co-authored 1 publications.
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Papers
Spatially resolved multiomics of human cardiac niches
Kazumasa Kanemaru,J. C. Cranley,Daniele Muraro,Antonio M. A. Miranda,J. Patrick Pett,Monika Litviňuková,Natsuhiko Kumasaka,Siew Yen Ho,Krzysztof Polanski,Laura Richardson,Lukasz Mach,Monika Dabrowska,Nathan Richoz,Sam N. Barnett,Shani Perera,Anna Wilbrey-Clark,Carlos Talavera-López,I. Mulas,Krishnaa T. Mahbubani,Liam Bolt,Lira Mamanova,Liz Tuck,Lu Wang,Margaret M. Huang,M. Julieta Del Prete,Sophie Pritchard,J Dark,Kourosh Saeb-Parsy,Minal Patel,Menna R. Clatworthy,N. Hübner,Rasheda A. Chowdhury,Michela Noseda,Sarah A. Teichmann +33 more
TL;DR: In this paper , the authors combine single-cell and spatial transcriptomic data to discover cellular niches within eight regions of the human heart, including the sinoatrial node and the epicardium.
Multiomic analysis reveals developmental dynamics of the human heart in health and disease
J. C. Cranley,Kazumasa Kanemaru,Semih Bayraktar,Vincent Knight-Schrijver,J. Patrick Pett,Krzysztof Polanski,Monika Dabrowska,I. Mulas,Laura Richardson,Claudia I. Semprich,Rakeshlal Kapuge,Shani Perera,Xiaoling He,Siew Yen Ho,Nadav Yayon,Liz Tuck,Kenny Roberts,Jack A. Palmer,Hongorzul Davaapil,L. Gambardella,Minal Patel,Richard Tyser,Sanjay Sinha,Sarah A. Teichmann +23 more
TL;DR: This multiomic analysis of human heart development reveals cell type specification, spatial organisation, and lineage relationships, including the origin of cardiac-resident macrophages and distinct characteristics of foetal pacemaker cells, with implications for heart disease and development.
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Author Correction: Spatially resolved multiomics of human cardiac niches.
Kazumasa Kanemaru,J. C. Cranley,Daniele Muraro,Antonio M. A. Miranda,S. Y. Ho,Anna Wilbrey-Clark,J. Patrick Pett,Krzysztof Polanski,Laura Richardson,Monika Litviňuková,Natushiko Kumasaka,Yue Qin,Zuzanna Jablonska,Claudia I. Semprich,Lukas Mach,Monika Dabrowska,Nathan Richoz,Liam Bolt,Lira Mamanova,R. Kapuge,Sam N. Barnett,Shani Perera,Carlos Talavera-López,I. Mulas,Krishnaa T. Mahbubani,Liz Tuck,Margaret M Huang,M. Julieta Del Prete,Sophie Pritchard,J. Dark,Kourosh Saeb-Parsy,Menna R. Clatworthy,Norbert Hübner,Rasheda A Chowdhury,M. Noseda,Sarah A. Teichmann +35 more
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A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Nusayhah Gopee,Ni Huang,Bayanne Olabi,Chloe Admane,Rachel A. Botting,April Rose Foster,Fereshteh Torabi,Elena Winheim,Dinithi Sumanaweera,Issac Goh,Mohiuddin Miah,Emily Stephenson,Win Min Tun,Pejvak Moghimi,Ben Rumney,Peng He,Sid Lawrence,Kenny Roberts,Keval Sidhpura,Justin Englebert,Laura Jardine,Gary Reynolds,Antony Rose,Clarisse Ganier,Vicky Rowe,Sophie Pritchard,I. Mulas,J. Fletcher,Dorin Popescu,Elizabeth Poyner,Anna Dubois,Andrew Filby,Steven Lisgo,Roger A. Barker,Jong-Eun Park,Roser Vento-Tormo,Phuong Ahn Le,Sara A. Serdy,Jin Kim,CiCi Deakin,Jiyoon Lee,Marina T. Nikolova,Neil Rajan,Stephane Ballereau,Tong Li,Josh Moore,Dave Horsfall,Daniela Basurto Lozada,Edel.A. O’Toole,Barbara Treutlein,Omer Ali Bayraktar,Maria Kasper,Pavel Mazin,Laure Gambardella,Karl Koehler,Sarah A. Teichmann,Muzlifah Haniffa +56 more
TL;DR: It is revealed that crosstalk between non-immune and immune cells underpins formation of hair follicles, has implications for scarless wound healing, and is critical for skin angiogenesis.
A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity
Grant de Jong,Fani Memi,Tannia Gracia,Olga Lazareva,Oliver Gould,Alexander Aivazidis,Manas Dave,Qianqian Zhang,Melanie Jensen,Ahmet Sureyya Rifaioglu,Joao D. Barros-Silva,Sabine Eckert,Yvette Wood,Elizabeth Tuck,Sezgin Er,Henry Marshall,Kenny Roberts,Andrew L. Trinh,Shreya Rai,Tyler Shaw,Ágnes Oszlánczi,Hayden Powell,Robert Petryszak,Zoi Katsirea,Irfan Mamun,I. Mulas,Annelies Quaegebeur,Mayen Briggs,Stanislaw Makarchuk,Jessica Cox,Jimmy Tsz Hang Lee,Laura Rueda,Manu Saraswat,Harry J C J Bulstrode,Adam Young,Minal Patel,Tarryn Porter,Elena Prigmore,Moritz Mall,Julio Saez-Rodriguez,James Briscoe,David H. Rowitch,Richard Mair,Sam Behjati,O. Stegle,Omer Ali Bayraktar +45 more