I. Lutzmann
Ludwig Maximilian University of Munich
9 Papers
16 Citations
I. Lutzmann is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Xenotransplantation & Heart transplantation. The author has an hindex of 3, co-authored 9 publications.
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Papers
Consistent success in life-supporting porcine cardiac xenotransplantation
Matthias Längin,Tanja Mayr,Bruno Reichart,Sebastian Michel,Stefan Buchholz,Sonja Guethoff,Alexey Dashkevich,Andrea Baehr,Stefanie Egerer,Andreas Bauer,Maks Mihalj,Alessandro Panelli,Lara Issl,Jiawei Ying,Ann Kathrin Fresch,Ines Buttgereit,Maren Mokelke,Julia Radan,Fabian Werner,I. Lutzmann,Stig Steen,Trygve Sjöberg,Audrius Paskevicius,Liao Qiuming,Riccardo Sfriso,Robert Rieben,Maik Dahlhoff,Barbara Kessler,Elisabeth Kemter,Mayuko Kurome,Valeri Zakhartchenko,Katharina Klett,Katharina Klett,Rabea Hinkel,Rabea Hinkel,Christian Kupatt,Almuth Falkenau,Simone Reu,Reinhard Ellgass,Rudolf Herzog,Uli Binder,Günter Wich,Arne Skerra,David Ayares,Alexander Kind,Uwe Schönmann,Franz-Josef Kaup,Christian Hagl,Eckhard Wolf,Nikolai Klymiuk,Paolo Brenner,Jan-Michael Abicht +51 more
TL;DR: It is shown that α1,3-galactosyltransferase-knockout pig hearts that express human CD46 and thrombomodulin require non-ischaemic preservation with continuous perfusion and post-transplantation growth control to ensure long-term orthotopic function of the xenograft in baboons, the most stringent preclinical xenotransplantation model.
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Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation.
Matthias Längin,Tanja Mayr,Bruno Reichart,Sebastian Michel,Stefan Buchholz,Sonja Guethoff,Alexey Dashkevich,Andrea Baehr,Stefanie Egerer,Andreas Bauer,Maks Mihalj,Alessandro Panelli,Lara Issl,Jiawei Ying,Ann Kathrin Fresch,Ines Buttgereit,Maren Mokelke,Julia Radan,Fabian Werner,I. Lutzmann,Stig Steen,Trygve Sjöberg,Audrius Paskevicius,Liao Qiuming,Riccardo Sfriso,Robert Rieben,Maik Dahlhoff,Barbara Kessler,Elisabeth Kemter,Mayuko Kurome,Valeri Zakhartchenko,Katharina Klett,Katharina Klett,Rabea Hinkel,Rabea Hinkel,Christian Kupatt,Almuth Falkenau,Simone Reu,Reinhard Ellgass,Rudolf Herzog,Uli Binder,Günter Wich,Arne Skerra,David Ayares,Alexander Kind,Uwe Schönmann,Franz-Josef Kaup,Christian Hagl,Eckhard Wolf,Nikolai Klymiuk,Paolo Brenner,Jan-Michael Abicht +51 more
TL;DR: In this Letter, Mayuko Kurome and Valeri Zakhartchenko have been added to the author list (affiliated with Institute of Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Munich, Germany).
Study for Comparison of CD40-mAb and CD40L-Ab Costimulation Blockade after Life-Supporting Orthotopic Cardiac Xenotransplantation of Multi-Transgenic Pig Hearts into Baboons with a Worldwide First Successful Long-Term Survival
Paolo Brenner,Bruno Reichart,Tanja Mayr,Matthias Längin,Sonja Güthoff,Stefan Buchholz,Sebastian Michel,I. Lutzmann,Fabian Werner,Andreas Bauer,Nikolai Klymiuk,Eckhard Wolf,Keith A. Reimann,Walter Hermanns,David Ayares,Christian Hagl,Stig Steen,Jan-Michael Abicht +17 more
TL;DR: Total survival in this important life-supporting orthotopic model was significantly prolonged with a less toxic IS and better quality of life, and progress on the way to a long-term survival of 2 -3 months, which is necessary for first clinical cardiac xenotransplantations.
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40 Days Survival after Orthotopic Cardiac Xenotransplantation of Multi-Transgenic Pig Hearts in a Pig-to-Baboon Model with CD40mAb or CD40L Costimulation Blockade and Xenograft Preservation using “Steens” Cold Blood Cardioplegia Perfusion
Paolo Brenner,Tanja Mayr,Bruno Reichart,Sonja Guethoff,Stefan Buchholz,Alexander Dashkevich,Sebastian Michel,I. Lutzmann,Fabian Werner,Andreas Bauer,Nikolai Klymiuk,Eckhard Wolf,Muhammad Mohiuddin,Keith A. Reimann,Walter Hermanns,David Ayares,Christopher G.A. McGregor,Christian Hagl,Stig Steen,Jan-Michael Abicht +19 more
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Worldwide First Successful Long-term Survival after Orthotopic Cardiac Xenotransplantation of Multitransgenic Pig Hearts into Baboons Using a CD40mAb or CD40L Costimulation Blockade
Paolo Brenner,Bruno Reichart,Tanja Mayr,Matthias Längin,Sonja Guethoff,Stefan Buchholz,Alexey Dashkevich,Sebastian Michel,I. Lutzmann,Fabian Werner,Andreas Bauer,Nikolai Klymiuk,E. Wolf,Keith A. Reimann,Walter Hermanns,D. Ayares,Christian Hagl,Stig Steen,J.-M. Abicht +18 more
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