I. de Boer
11 Papers
I. de Boer is an academic researcher. The author has contributed to research in topics: Internal medicine & Medicine. The author has co-authored 7 publications.
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Papers
316-OR: ADA Presidents' Select Abstract: Structural Lesions on Kidney Biopsy in Youth-Onset Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D)
Viji Nair,Abhijit S. Naik,Fadhl M. Al-Akwaa,Jennifer A. Schaub,Tim Vigers,Markus Bitzer,Laura Pyle,Frank C. Brosius,P. Ladd,Viral N. Shah,Kalie L. Tommerdahl,Kumar Sharma,I. de Boer,Pierre-Jean Saulnier,Helen C. Looker,Robert G. Nelson,Jeffrey B. Hodgin,Petter Bjornstad +17 more
TL;DR: In this article , the authors compared kidney structural lesions in participants with youth-onset T2D and T1D to determine if youth-onset T2DM was associated with greater early tissue injury.
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1159-P: Impaired Insulin Sensitivity Relates to Preclinical Biomarkers of Neurodegenerative Disease in Young Adults With and Without Type 1 Diabetes (T1D)
Carissa Vinovskis,Tim Vigers,Meghan E Pauley,Janet K. Snell-Bergeon,Alexis MacDonald,Kalie L. Tommerdahl,Daniël H. van Raalte,I. de Boer,Robert G. Nelson,Laura Pyle,Kristen J. Nadeau,Petter Bjornstad +11 more
TL;DR: In this paper , the authors examined the relationship between impaired insulin sensitivity and preclinical biomarkers of AD/ADRD in 30 young adults with T1D (age 23±3 years, diabetes duration 13±5 years, 53% female, HbA1c 7.9±1.3, BMI: 23±2).
1095-P: Proteomic Analyses Identify Novel Predictors of Loss of Glycemic Control in Youth-Onset Type 2 Diabetes
Tim Vigers,Laure El Ghormli,I. de Boer,Robert G. Nelson,Kumar Sharma,Sushrut S. Waikar,Neil H. White,Kalie L. Tommerdahl,Lori M.B. Laffel,Amy S. Shah,Kimberly L. Drews,Justin R. Ryder,Rose Gubitosi-Klug,Petter Bjornstad,Laura Pyle +14 more
TL;DR: In this paper , the authors measured 7604 Aptamers in 374 baseline plasma samples from the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) study, using the SomaScan 7K Proteomic (SomaLogic) platform.
406-P: Spatial Metabolomics of Human Kidney Tissues Reveal Impaired Tricarboxylic Acid (TCA) Cycle Turnover in Type 1 Diabetes (T1D)
Guanshi Zhang,Ian Tamayo,Tim Vigers,Kalie L. Tommerdahl,Robert G. Nelson,P. Ladd,Theodore Alexandrov,I. de Boer,Jennifer A. Schaub,Kristen J. Nadeau,Viji Nair,Fadhl M. Al-Akwaa,Phillip J. McCown,Abhijit V. Naik,Laura Pyle,Gabriel Richard,Matthias Kretzler,Petter Bjornstad,Kumar Sharma +18 more
TL;DR: In this article , spatial metabolomics analyses of the kidney tissue were conducted to further explore perturbations in kidney oxidative metabolism in T1D, showing impaired TCA cycle turnover using 11C acetate PET and lower proximal tubular transcripts.
9-OR: Insulin Resistance (IR) and Kidney Oxidative Metabolism in People with Type 1 Diabetes (T1D)
Gabriel Richard,Guanshi Zhang,Lynette M Driscoll,Kalie L. Tommerdahl,Jennifer A. Schaub,Abhijit V. Naik,Viji Nair,Alexis MacDonald,Susan P. Gross,Viral N. Shah,Laura Pyle,Tim Vigers,Janet K. Snell-Bergeon,I. de Boer,Daniël H. van Raalte,Lu-Ping Li,Pottumarthi V. Prasad,P. Ladd,David Z.I. Cherney,Phillip J. McCown,Fadhl M. Al-Akwaa,Matthias Kretzler,Kumar Sharma,Frank C. Brosius,Robert G. Nelson,Kristen J. Nadeau,Petter Bjornstad +26 more
TL;DR: In this paper , the authors showed that kidney oxidative metabolism is impaired in young adults with Type 1 diabetes and is linked to lower whole-body insulin sensitivity (IS) and lower cortical k2.