I. Carmichael
University of Melbourne
7 Papers
I. Carmichael is an academic researcher from University of Melbourne. The author has contributed to research in topics: Biology & Chemistry. The author has an hindex of 1, co-authored 1 publications.
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Papers
Characterising seizure development, behavioural comorbidities and neuroinflammation in a self-sustained electrical status epilepticus model of mesial temporal lobe epilepsy in C57BL/6J mice
Peravina Thergarajan,Matthew R. Hudson,I. Carmichael,Jerome Clasadonte,Stefanie Dedeurwaerdere,Terence J. O'Brien,Nigel C. Jones,Idrish Ali +7 more
TL;DR: In this paper , a self-sustained electrical status epilepticus (SSSE) was induced in C57BL/6J mice via prolonged electrical stimulation through a bipolar electrode implanted in the ventral hippocampus.
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Abstract 3491: New targets and new approaches for multiple myeloma: Extracellular vesicles as functional liquid biomarkers
Antonia Reale,Tiffany Khong,Rong Xu,I. Carmichael,Haoyun Fang,Nicholas Bingham,Sridurga Mithraprabhu,Maoshan Chen,Malarmathy Ramachandran,David W. Greening,Andrew Spencer +10 more
TL;DR: The characterization and proteomic profiling of disease-specific circulating sEV as a biomarker discovery strategy may provide translational applications in MM and MM-sEV may play an important role in disease progression by re-programming the tumor microenvironment.
Abstract 2366: Myeloma-derived circulating extracellular vesicles affect human stromal cell behaviour and promote tumor progression: A multi-omic approach
Antonia Reale,Rong Xu,I. Carmichael,Haoyun Fang,Tiffany Khong,Nicholas Bingham,Malarmathy Ramachandran,Maoshan Chen,David W. Greening,Andrew Spencer +9 more
TL;DR: Hoshino et al. as mentioned in this paper showed that small extracellular vesicles (EV) derived from plasma of myeloma (MM) patients (MM-EV) promoted adhesion of human MM cell lines (HMCL), with preliminary proteomic profiling of MM- vs healthy donors HD-EV revealing enrichment of factors implicated in cell migration and adhesion.
Multiple Myeloma-Derived Circulating Extracellular Vesicles Affect Normal Human Stromal Cell Behaviour and Promote Tumor Progression: A Multi-Omic Approach
Antonia Reale,I. Carmichael,Rong Xu,Haoyun Fang,Jaynish S. Shah,Tiffany Khong,Nicholas Bingham,Malarmathy Ramachandran,Maoshan Chen,David W. Greening,Andrew Spencer +10 more
TL;DR: In this article , the authors demonstrate that circulating small extracellular vesicles (sEV) enriched from myeloma (MM) patients induce the formation of a supportive tumour microenvironment (TME) and pre-metastatic sites/niches.
Bacterial colonization and biofilm development on minimally processed vegetables.
TL;DR: This study investigates the progression of biofilm formation from leaf colonization, and will assist in characterising the critical mechanisms of plant/host interaction and facilitate the development of improved preservation, sanitising and packaging strategies for minimally processed vegetable products.