Amyloid-like protein nanofibrous membranes as a sensing layer infrastructure for the design of mass-sensitive biosensors.

Cardiac troponin T (cTnT) detection has been the focus of increased interest due to its role in myocardial infarction diagnosis. In this study, we report a relatively low coat technique to detect cTnT using a quartz crystal microbalance (QCM) sensor. A sensitive detection is achieved by introducing a QCM surface with a carboxylic polyvinyl chloride immobilization layer. The surface morphologies of this polymer film under varied deposition thickness have been investigated by field emission scanning electron microscopy and atomic force microscopy. A cTnT detection result from a modified QCM surface can be obtained within a short response time by a direct detection of the immunoreaction and a direct conversion of mass accumulation into a frequency shift, representing a measurable electrical signal. The relationship between the cTnT concentration and the response current from a QCM sensor shows detectability at the concentration of cTnT as low as 5 ng/ml.

Cardiac troponin T detection using polymers coated quartz crystal microbalance as a cost-effective immunosensor.

Surface topography and optical studies on polystyrene (PS) coated l-Lysine monohydrochloride dihydrate (L-LMHCl) single crystals

Alcohol vapour sensors can be used in many fields, such as food quality monitoring, etc. Herein, we developed an alcohol vapour sensor based on the quartz crystal microbalance (QCM) technology. A m...

Novel alcohol vapour sensor based on the mixed-ligand modified MOF-199 coated quartz crystal microbalance

The influence of the nature of sorption phases on the microweighing parameters of volatile organic compounds sorbed from gases and vapors is investigated using microstructural methods. The mechanism of interaction between nitrogen-containing compounds and universal polymeric and solid-phase specific sorbents is found. The roughness parameters of piezoelectric-resonator electrodes are estimated before and after the deposition of thin sorbent films and during the sorption and desorption of nitrogen-containing compound vapors. Recommendations on how to employ piezoelectric resonators with films for identifying different compounds of gas and air mixtures are presented.

Microstructural investigations of sorption layers in mass-sensitive sensors for the detection of nitrogen-containing compounds

Polymer films as sensitive coatings for quartz crystal microbalance sensors array

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Polymer films as sensitive coatings for quartz crystal microbalance sensors array