Hyun Jung Oh
Harvard University
16 Papers
113 Citations
Hyun Jung Oh is an academic researcher from Harvard University. The author has contributed to research in topics: Signal transduction & XIST. The author has an hindex of 11, co-authored 16 publications. Previous affiliations of Hyun Jung Oh include Howard Hughes Medical Institute & KAIST.
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Papers
TERRA RNA Antagonizes ATRX and Protects Telomeres
Hsueh-Ping Chu,Catherine Cifuentes-Rojas,Catherine Cifuentes-Rojas,Barry Kesner,Barry Kesner,Eric Aeby,Eric Aeby,Hun-Goo Lee,Hun-Goo Lee,Chunyao Wei,Chunyao Wei,Hyun Jung Oh,Hyun Jung Oh,Myriam Boukhali,Wilhelm Haas,Jeannie T. Lee,Jeannie T. Lee +16 more
TL;DR: It is concluded that TERRA functions as an epigenomic modulator in trans and as an essential regulator of telomeres in cis and in trans to genic targets.
232
A crucial role of WW45 in developing epithelial tissues in the mouse
Joo-Hyeon Lee,Tae Shin Kim,Taehong Yang,Bon-Kyoung Koo,Sangphil Oh,Kwang-Pyo Lee,Hyun Jung Oh,Sang-Hee Lee,Young-Yun Kong,Jin Man Kim,Dae-Sik Lim +10 more
TL;DR: This article showed that WW45 is a key mediator of MST1 signalling in the coordinate coupling of proliferation arrest with terminal differentiation for proper epithelial tissue development in mammals, and showed that W45 is required for MST 1 activation and translocation to the nucleus for subsequent LATS 1/2 activation upon differentiation signal.
Role of the Tumor Suppressor RASSF1A in Mst1-Mediated Apoptosis
Hyun Jung Oh,Kyung Kwon Lee,Su Jung Song,Mi Sun Jin,Min Sup Song,Joo Hyun Lee,Chang Rak Im,Jie-Oh Lee,Shin Yonehara,Dae-Sik Lim +9 more
TL;DR: Findings indicate that RASSF1A facilitates Mst1 activation and thereby promotes apoptosis induced by death receptor signaling.
199
SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X.
TL;DR: A stepwise model for Xi folding is presented, where SMCHD1 attenuates a hidden layer of Xi architecture to facilitate Xist spreading and erosion of heterochromatic silencing.
166
The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex
TL;DR: This work shows that the tumour suppressor RASSF1A regulates G1–S cell‐cycle progression in a p53‐dependent manner by promoting MDM2 self‐ubiquitination and preventing p53 degradation, and reveals a new and important function for RASSf1A in regulating the p53–MDM2 pathway.