Hyewon Jeon
New Generation University College
8 Papers
59 Citations
Hyewon Jeon is an academic researcher from New Generation University College. The author has contributed to research in topics: Pharmacokinetics & Pharmacodynamics. The author has an hindex of 6, co-authored 7 publications. Previous affiliations of Hyewon Jeon include Seoul National University.
Chat about Author
Papers
Glucocorticoid-induced tumor necrosis factor receptor-related protein co-stimulation facilitates tumor regression by inducing IL-9-producing helper T cells
Il-Kyu Kim,Byung Seok Kim,Choong Hyun Koh,Jae Won Seok,Jun Seok Park,Kwang Soo Shin,Eun Ah Bae,Ga Eun Lee,Hyewon Jeon,Jaebeom Cho,Yujin Jung,Daehee Han,Byoung S. Kwon,Ho-Young Lee,Yeonseok Chung,Yeonseok Chung,Chang-Yuil Kang +16 more
TL;DR: GITR co-stimulation mediates antitumor immunity by promoting TH9 cell differentiation and enhancing CTL responses and thus provide a mechanism of action for GITR agonist–mediated cancer immunotherapies.
151
Apple juice greatly reduces systemic exposure to atenolol
Hyewon Jeon,In-Jin Jang,Seung Hwan Lee,Kyoichi Ohashi,Tsutomu Kotegawa,Ichiro Ieiri,Joo Youn Cho,Seo Hyun Yoon,Sang-Goo Shin,Kyung Sang Yu,Kyoung Soo Lim +10 more
TL;DR: Apple juice markedly reduced systemic exposure to atenolol and the genetic variation of SLCO2B1 c.1457C>T had a minimal effect on the pharmacokinetics of atenorol when the drug was administered with water or apple juice.
Assessment of the drug-drug interactions between fimasartan and hydrochlorothiazide in healthy volunteers.
Hyewon Jeon,Kyoung Soo Lim,Kwang-Hee Shin,JaeWoo Kim,JaeWoo Kim,Seo Hyun Yoon,Joo Youn Cho,Sang-Goo Shin,In-Jin Jang,Kyung Sang Yu +9 more
TL;DR: Coadministration of fimasartan increased the urinary excretion of HCTZ and urine volume, but these observations are unlikely to have any clinical relevance.
30
Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men.
TL;DR: Tolvaptan showed dose-linear pharmacokinetic characteristics regarding area under the concentration–time curve and resulted in substantial, dose-dependent aquaresis in healthy Korean men.
25
Relationship Between Absolute Neutrophil Count Profiles and Pharmacokinetics of DA-3031, a Pegylated Granulocyte Colony-Stimulating Factor (Pegylated-G-CSF): A Dose Block-Randomized, Double-Blind, Dose-Escalation Study in Healthy Subjects
Li Young Ahn,Kwang-Hee Shin,Kwang-Hee Shin,Kyoung Soo Lim,Tae Eun Kim,Hyewon Jeon,Seo Hyun Yoon,Joo Youn Cho,Sang-Goo Shin,In-Jin Jang,Kyung Sang Yu +10 more
TL;DR: DA-3031 showed non-linear pharmacodynamic and pharmacokinetic profiles and an extended duration of action compared with non-modified filgrastim, without unexpected toxicities in healthy subjects.
8