Huiying Sheng
Guangzhou Medical University
34 Papers
84 Citations
Huiying Sheng is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Medicine & Gene mutation. The author has an hindex of 7, co-authored 30 publications.
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Papers
The EGFR-P38 MAPK axis up-regulates PD-L1 through miR-675-5p and down-regulates HLA-ABC via hexokinase-2 in hepatocellular carcinoma cells
Zongcai Liu,Fen Ning,Yanna Cai,Huiying Sheng,Ruidan Zheng,Xi Yin,Zhikun Lu,Ling Su,Xiaodan Chen,Chunhua Zeng,Haifang Wang,Li Liu +11 more
TL;DR: In this paper, the authors investigated the impact of EGFR signaling on PD-L1 and human leukocyte antigen class-I (HLA-I) expression in HCC cells and its underlying mechanisms.
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Clinical and molecular characteristics of patients with Gaucher disease in Southern China.
Yuyu Feng,Yonglan Huang,Chengfang Tang,Hao Hu,Xiaoyuan Zhao,Huiying Sheng,Wen Zhang,Min-Yi Tan,Ting Xie,Jipeng Zheng,Zongcai Liu,Xueying Su,Yongxian Shao,Xiuzhen Li,Jing Cheng,Xiaojian Mao,Li Liu +16 more
TL;DR: It is revealed that type 1 GD tends to present with a severe phenotype among southern Chinese, and L444P was the most prevalent mutation and L 444P homozygous genotype was associated with severe type 1GD.
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Epidermal growth factor and tumor necrosis factor α cooperatively promote the motility of hepatocellular carcinoma cell lines via synergistic induction of fibronectin by NF-κB/p65.
Zongcai Liu,Fen Ning,Haifang Wang,Danyang Chen,Yanna Cai,Huiying Sheng,Gendie E. Lash,Li Liu,Jun Du +8 more
TL;DR: Findings highlight the crosstalk between EGF and TNFα in promoting HCC, and provide potential targets for HCC prevention and treatment.
23
Clinical and molecular analysis of 6 Chinese patients with isoleucine metabolism defects: identification of 3 novel mutations in the HSD17B10 and ACAT1 gene.
TL;DR: DNA diagnosis played an important role in distinguishing between these two disorders, indicating that the multifunction of HSD10, especially neurosteroid metabolic activity, other than only enzymatic degradation of isoleucine, is involved in the pathogenesis of H SD10 deficiency.
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Molecular diagnosis of maturity-onset diabetes of the young in a cohort of Chinese children.
Aijing Xu,Yunting Lin,Huiying Sheng,Jing Cheng,Huifen Mei,Tzer Hwu Ting,Chunhua Zeng,Cuili Liang,Wen Zhang,Cuiling Li,Xiuzhen Li,Li Liu +11 more
TL;DR: The purpose of this study was to investigate the molecular basis of maturity‐onset diabetes of the young by whole‐exome sequencing (WES) and estimate the frequency and describe the clinical characteristics of MODY in southern China.
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