Huirong Huang
Wenzhou Medical College
12 Papers
Huirong Huang is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Medicine & Drug delivery. The author has an hindex of 4, co-authored 5 publications.
Chat about Author
Papers
Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage
TL;DR: The development of sustained-release drug delivery systems (DDSs) for OA may be an attractive strategy to prevent rapid drug clearance and improve the half-life of a drug at the joint cavity to promote the development of effective OA drugs in the future.
76
Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy.
Longfa Kou,Huirong Huang,Ying Zhong Tang,Meng Sun,Yingtao Li,Jianing Wu,Shimin Zheng,Xin Zhao,Daosen Chen,Zucheng Luo,Xiaolei Zhang,Qing Yao,Ruijie Chen +12 more
TL;DR: In this paper , a novel opsonization trapping strategy for osteoarthritis drug delivery and treatment is proposed, which transforms a normal nanoparticle into an opsonized attractant to target and regulate macrophage polarization.
52
Tumor Microenvironment-Responsive, Multistaged Liposome Induces Apoptosis and Ferroptosis by Amplifying Oxidative Stress for Enhanced Cancer Therapy.
Longfa Kou,Rui Sun,Xinyu Jiang,Xinlu Lin,Huirong Huang,Shihui Bao,Youting Zhang,Chao Li,Ruijie Chen,Qing Yao +9 more
TL;DR: The results suggested that the tumor microenvironment-responsive multistaged nanoplatform, DS@MA-LS, has excellent potential for optimal drug delivery and enhanced cancer treatment.
51
Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor
Zhiwei Chen,Aimin Cai,Hailun Zheng,Huirong Huang,Rui Sun,Xiao Cui,Weijian Ye,Qing Yao,Ruijie Chen,Longfa Kou +9 more
- 13 May 2020
TL;DR: This study implicates Carbidopa for the first time in effective suppression of prostate cancer via a mechanism, involving AHR-mediated proteasomal degradation of AR.
A Biomimetic Nanoparticle Exerting Protection Against Acute Liver Failure by Suppressing CYP2E1 Activity and Scavenging Excessive ROS.
Qing Yao,Ying Zhong Tang,Zewei Jiang,Shiming Zheng,Meng Sun,Ruijie Lu,Tuyue Sun,Huirong Huang,Xinyu Jiang,GuangYong Lin,Longfa Kou,Ruijie Chen +11 more
TL;DR: In this article , a carrier-free and bilirubin dotted nanoparticle (B/BG@N) was developed to reduce the production of NAPQI and ROS.
9