Huiping Lu
Fudan University
9 Papers
1 Citations
Huiping Lu is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Nanoparticle. The author has an hindex of 3, co-authored 5 publications.
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Papers
Sequential delivery of nanoformulated α-mangostin and triptolide overcomes permeation obstacles and improves therapeutic effects in pancreatic cancer.
Jingxian Feng,Minjun Xu,Jiahao Wang,Songlei Zhou,Y. P. Liu,Shanshan Liu,Yukun Huang,Yu Chen,Liang Chen,Qingxiang Song,Jingru Gong,Huiping Lu,Xiaoling Gao,Jun Chen +13 more
TL;DR: Wang et al. as discussed by the authors developed a CAFs-targeting biodegradable polymer nanoparticle (CRE-NP) coated with CREKA peptide and loaded with TCM α-mangostin (α-M) to modulate tumor microenvironment by interfering of TGF-β/Smad signaling pathway.
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Metformin and Docosahexaenoic Acid Hybrid Micelles for Premetastatic Niche Modulation and Tumor Metastasis Suppression
Tianze Jiang,Liang Chen,Yukun Huang,Jiahao Wang,Minjun Xu,Songlei Zhou,Xiao Gu,Yu Chen,Kaifan Liang,Yuanyuan Pei,Qingxiang Song,Shanshan Liu,Fenfen Ma,Huiping Lu,Xiaoling Gao,Jun Chen +15 more
TL;DR: The findings here provide proof of concept that the modulation of the premetastatic niche with targeted anti-inflammatory agents provides a potent platform and a safe and clinical translational option for the suppression of tumor metastasis.
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Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy.
Minjun Xu,Kaili Hu,Y. P. Liu,Yukun Huang,Yukun Huang,Shanshan Liu,Yu Chen,Dayuan Wang,Songlei Zhou,Qian Zhang,Ni Mei,Huiping Lu,Fengan Li,Xiaoling Gao,Jun Chen +14 more
TL;DR: Wang et al. as discussed by the authors designed a systemic metastasis-targeted nanotherapeutic (H@CaPP) composed of an anti-inflammatory agent, piceatannol, and anti-thrombotic agent, low molecular weight heparin, to hinder the multiple steps of tumor metastasis.
Neutrophil-Biomimetic "Nanobuffer" for Remodeling the Microenvironment in the Infarct Core and Protecting Neurons in the Penumbra via Neutralization of Detrimental Factors to Treat Ischemic Stroke.
Shanshan Liu,Jianpei Xu,Yipu Liu,Yang You,Laozhi Xie,Shiqiang Tong,Yu Chen,Kaifan Liang,Songlei Zhou,Fengan Li,Zhuang Tang,Ni Mei,Huiping Lu,Xiaolin Wang,Xiaoling Gao,Jun Chen +15 more
TL;DR: Systematic evaluations show significant decrease of detrimental factors in the core and the penumbra, reduced infarct volume, and improved neurological recovery compared to the untreated group of stroke rats.
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Interplay between Liposomes and IgM: Principles, Challenges, and Opportunities.
TL;DR: In this article , the intricate relationship between liposomes and their biological environments has been summarized, with an emphasis on the regulatory effects of immunoglobulin M on in vivo performance.
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