Huiling Han
9 Papers
28 Citations
Huiling Han is an academic researcher. The author has contributed to research in topics: Hepcidin & Erythroferrone. The author has an hindex of 3, co-authored 9 publications.
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Papers
A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis
Patrick Gutschow,Paul J. Schmidt,Huiling Han,Vaughn Ostland,Thomas B. Bartnikas,Michael A. Pettiglio,Carolina Herrera,James Butler,Elizabeta Nemeth,Tomas Ganz,Mark D. Fleming,Mark Westerman +11 more
TL;DR: A competitive, enzyme-linked immunosorbent assay that quantifies hepcidin-1 in mouse serum and urine exhibits a biologically relevant lower limit of detection, high precision, and excellent linearity and recovery is described and validated.
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The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry.
Melanie Castro-Mollo,Sakshi Gera,Marc Ruiz-Martinez,Maria Feola,Anisa Gumerova,Marina Planoutene,Cara Clementelli,Veena Sangkhae,Carla Casu,Se-Min Kim,Vaughn Ostland,Huiling Han,Elizabeta Nemeth,Robert E. Fleming,Stefano Rivella,Daria Lizneva,Tony Yuen,Mone Zaidi,Yelena Ginzburg +18 more
TL;DR: In this paper, the authors employ comprehensive skeletal phenotyping analyses as well as functional assays in vitro to address mechanistically the function of Erythroblast erythroblasts (ERFE) in bone.
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The Hepcidin Regulator Erythroferrone is a New Member of the Erythropoiesis-Iron-Bone Circuitry
Melanie Castro-Mollo,Sakshi Gera,Marc Ruiz Martinez,Maria Feola,Anisa Gumerova,Marina Planoutene,Cara Clementelli,Veena Sangkhae,Carla Casu,Se-Min Kim,Vaughn Ostland,Huiling Han,Elizabeta Nemeth,Robert E. Fleming,Stefano Rivella,Daria Lizneva,Tony Yuen,Mone Zaidi,Yelena Ginzburg +18 more
TL;DR: In this paper, the authors reported that ERFE expression in osteoblasts is higher compared with erythroblasts, is independent of erythropoietin, and functional in suppressing hepatocyte hepcidin expression.
Patent
Anti-hepcidin antibodies and uses thereof
Mark Westerman,Vaughn Ostland,Huiling Han,Patrick Gutschow,Keith Westerman,Gordana Olbina +5 more
- 13 Mar 2014
TL;DR: In this paper, the use of humanized antibodies which specifically bind to hepcidin and regulate iron homeostasis for the treatment of a disease or condition associated with HE is discussed.
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A Novel Dual Monoclonal Sandwich ELISA for Human Erythroferrone
Huiling Han,Keith Westerman,Vaughn Ostland,Patrick Gutschow,Gordana Olbina,Jacqueline da Silva Guimarães,Juçara Gastaldi Cominal,Ana Maria de Souza,Ana Cristina Silva Pinto,Stefano Rivella,Yelena Ginzburg,Mark D. Fleming,Mark Westerman +12 more
TL;DR: The first dual monoclonal sandwich ELISA for serum measurement was developed to study the biological function and potential clinical applications of ERFE in humans and to test the concept that serum ERFE concentrations would be elevated in blood disorders associated with ineffective erythropoiesis.
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