Hui Ye
Wenzhou Medical College
6 Papers
31 Citations
Hui Ye is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Cancer & Cell growth. The author has an hindex of 4, co-authored 6 publications.
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Papers
Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells.
Rong Jin,Yiqun Xia,Qiuxiang Chen,Wulan Li,Dahui Chen,Hui Ye,Chengguang Zhao,Xiaojing Du,Dengjian Shi,Jianzhang Wu,Guang Liang +10 more
TL;DR: The asymmetric mono-carbonyl analog of curcumin Da0324 exhibited significantly improved antigastric cancer activity and may be a promising NF-κB inhibitor for the selective targeting of cancer cells.
A novel FGF2 antagonist peptide P8 with potent antiproliferation activity.
Lei Fan,Hang Xie,Lingzi Chen,Hui Ye,Shilong Ying,Cong Wang,Xiaoping Wu,Xiaoping Wu,Wulan Li,Jianzhang Wu,Guang Liang,Xiaokun Li +11 more
TL;DR: A novel FGF2-binding short peptide (P8, PLLQATAGGGS-NH2) is identified using phage display technology and alanine scanning and implied that P8 peptide may develop as a multi-target antagonist peptide contributing to tumor treatment.
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A novel double carbonyl analog of curcumin induces the apoptosis of human lung cancer H460 cells via the activation of the endoplasmic reticulum stress signaling pathway.
Hui Ye,Xiaoyan Wei,Zhankun Wang,Shanshan Zhang,Jiye Ren,Song Yao,Lingyi Shi,Lizhu Yang,Peihong Qiu,Jianzhang Wu,Guang Liang +10 more
TL;DR: It is demonstrated that A17 has better stability and antitumor activity than curcumin in H460 cells via an ER stress-mediated mechanism and could be further explored as a potential anticancer agent for the treatment of human non-small cell lung cancer (NSCLC).
A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer.
Lei Fan,Wulan Li,Shilong Ying,Lingyi Shi,Zhe Wang,Gaozhi Chen,Hui Ye,Xiaoping Wu,Xiaoping Wu,Jianzhang Wu,Guang Liang,Xiaokun Li +11 more
TL;DR: It is proved that P32, which had a half-life in human plasma up to 12 h, enhanced stability and exerted strong inhibitory effect on FGF2-induced cell proliferation and invasion in human gastric cancer cell lines.
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Peptidomimetic suppresses proliferation and invasion of gastric cancer cells by fibroblast growth factor 2 signaling cascade blockage.
Wulan Li,Xiaojing Du,Qiuxiang Chen,Yanting Kang,Chaochao Xu,Lei Fan,Hui Ye,Shilong Ying,Lingyi Shi,Rong Jin,Jianzhang Wu,Guang Liang,Xiaokun Li +12 more
TL;DR: A novel FGF2 inhibitor is presented that could exert improved anticancer effect in GC in vitro and possessed high affinity with F GF2 and a longer half-life in vitro.
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