Hui Wang
Nankai University
9 Papers
18 Citations
Hui Wang is an academic researcher from Nankai University. The author has contributed to research in topics: Pancreatic cancer & Metastasis. The author has an hindex of 6, co-authored 9 publications.
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Papers
Fractalkine/CX3CR1 induces apoptosis resistance and proliferation through the activation of the AKT/NF-κB cascade in pancreatic cancer cells.
TL;DR: The function of fractalkine is demonstrated in the activation of the AKT/NF‐κB/p65 signalling cascade and mediation of apoptosis resistance in pancreatic cancer cells, indicating its important role in the tumourigenesis of Pancreatic cancer.
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The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function
TL;DR: In this article, the effect of COL11A1/αI expression on the BCL-2/BAX signaling pathway was investigated in pancreatic cancer cells, and it was shown that the activation of the Akt/Akt axis induced a disruption of the mitochondrial transmembrane function, enabling mitochondria-mediated apoptotic evasion to promote chemoresistance.
LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity.
TL;DR: It is found that LAMC2 was responsible for generating the extracellular acidic conditions that mediated invasion of pancreatic cancer cells by activating Akt/NHE1 signaling.
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Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-κB signaling.
TL;DR: Artemin might be an effective and potent therapeutic target for pancreatic cancer metastasis, especially in perineural invasion, by regulating SDF‐1&agr;/CXCR4 axis.
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Tenascin-C Modulates Cell Cycle Progression to Enhance Tumour Cell Proliferation through AKT/FOXO1 Signalling in Pancreatic Cancer.
TL;DR: TNC exerts its activating effect on the proliferation of pancreatic cancer cells in vitro and in vivo through its functional target AKT/FOXO1/β-catenin.