Hui Li
University of Calgary
17 Papers
327 Citations
Hui Li is an academic researcher from University of Calgary. The author has contributed to research in topics: Ischemia & Medicine. The author has an hindex of 14, co-authored 16 publications. Previous affiliations of Hui Li include Cornell University & University of Ottawa.
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Papers
Continuing postischemic neuronal death in CA1: influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats.
TL;DR: In this paper, the authors assessed whether insult durations can vary the degree and maturation rate of CA1 injury and whether there are different ultrastructural features of death after brief or severe ischemia.
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A selective N-type Ca(2+)-channel blocker prevents CA1 injury 24 h following severe forebrain ischemia and reduces infarction following focal ischemia
Alastair M. Buchan,Stan Z. Gertler,Hui Li,Dong Xue,Zhi-Gao Huang,Karen E. Chaundy,Kimberley Barnes,Howard Lesiuk +7 more
TL;DR: Ca2+ fluxes through ω-conopeptide-sensitive N-type Ca2+ channels are critically involved in the pathogenesis of selective neuronal death up to 24 h after ischemia in the hippocampus and that this conopeptid protection extends, even when given late, to neocortical infarct reduction.
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•Journal Article
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Alastair M. Buchan,Howard Lesiuk,Kimberley Barnes,Hui Li,Z-Gao Huang,Karen E. Smith,Dong Xue +6 more
TL;DR: It is concluded that the AMPA receptor may play a more important role than the NMDA receptor in both selective ischemic necrosis of hippocampal neurons and in neocortical infarction.
109
Dehydroepiandrosterone (DHEA) reduces neuronal injury in a rat model of global cerebral ischemia
TL;DR: Treatment with a high dose, but not a low or moderate dose, of DHEA implantation reduces hippocampal CA(1) neuronal injury following severe but transient forebrain ischemia.
70
Failure to prevent selective CA1 neuronal death and reduce cortical infarction following cerebral ischemia with inhibition of nitric oxide synthase
TL;DR: High dose nitro-arginine caused an increase in hypertension in the spontaneously hypertensive rats and increased the severity of focal ischemia as measured by intra-ischemic regional cerebral blood flows.
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