Hugo Smith
2 Papers
Hugo Smith is an academic researcher. The author has contributed to research in topics: Internal medicine & Organ transplantation. The author has an hindex of 1, co-authored 1 publications.
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Papers
MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures
T. Sit,Rachael C. Feord,Alexander W. E. Dunn,Jeremi Chabros,David Oluigbo,Hugo Smith,Lance Burn,Elise Chang,Alessio Boschi,Yin Yuan,George M. Gibbons,Mahsa Khayat-Khoei,Francesco De Angelis,Erik Hemberg,M. Hemberg,Madeline A. Lancaster,Andras Lakatos,Stephen J. Eglen,Ole Paulsen,Susanna B. Mierau +19 more
TL;DR: A MATLAB MEA network analysis pipeline (MEA-NAP) for raw voltage time-series acquired from single- or multi-well MEAs, which can identify network-level effects of pharmacologic perturbation and/or disease-causing mutations and can provide a translational platform for revealing mechanistic insights and screening new therapeutic approaches.
Extracellular Vesicles as Drug Delivery Systems in Organ Transplantation: The Next Frontier
TL;DR: Extracellular vesicles are lipid bilayer-delimited nanoparticles excreted into the extracellular space by all cells as discussed by the authors, which carry a cargo rich in proteins, lipids and DNA, as well as a full complement of RNA species.