Hugo A. Katus
Heidelberg University
1553 Papers
9.9K Citations
Hugo A. Katus is an academic researcher from Heidelberg University. The author has contributed to research in topics: Medicine & Myocardial infarction. The author has an hindex of 107, co-authored 1496 publications. Previous affiliations of Hugo A. Katus include University Hospital Heidelberg.
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Papers
Therapeutic targeting of two-pore-domain potassium (K2P) channels in the cardiovascular system
Felix Wiedmann,Constanze Schmidt,Patrick Lugenbiel,Ingo Staudacher,Ann-Kathrin Rahm,Claudia Seyler,Patrick A. Schweizer,Hugo A. Katus,Dierk Thomas +8 more
TL;DR: The function, regulation and clinical significance of cardiovascular K(2P) channels are summarized in the present review, and therapeutic options are emphasized.
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Cardiac expression and atrial fibrillation-associated remodeling of K2P2.1 (TREK-1) K+ channels in a porcine model
Constanze Schmidt,Felix Wiedmann,Frank Tristram,Priya Anand,Wolfgang Wenzel,Patrick Lugenbiel,Patrick A. Schweizer,Hugo A. Katus,Dierk Thomas +8 more
TL;DR: Similarities between porcine and human K2P2.1 channels indicate that the pig may represent a valid model for mechanistic and preclinical studies and has potential implications for arrhythmia maintenance and antiarrhythmic therapy.
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•Journal Article
Abstract 15836: The Role of the Cholinergic Antiinflammatory Pathway in Murine Autoimmune Myocarditis
Christoph Leib,Stefan Göser,Doris Luthje,Renate Öttl,Stefan Zittrich,Gabriele Pfitzer,Hugo A. Katus,Ziya Kaya +7 more
TL;DR: In this article, the authors revealed an immuno-modulatory property of the vagus nerve referred to as the cholinergic anti-inflammatory pathway, and they applied chemical stimulation of the efferent arm of the vagus nerve.
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Extracellular matrix proteins and matrix metalloproteinases differ between various right and left ventricular sites in end-stage cardiomyopathies
Esther Herpel,Stephan Singer,Christa Flechtenmacher,Maria Pritsch,Falk-Udo Sack,Siegfried Hagl,Hugo A. Katus,Markus Haass,Herwart F. Otto,Philipp A. Schnabel +9 more
TL;DR: The results suggest that the distributions of ECM proteins and MMPs differ between the two ventricles in both end-stage DCM and ICM, giving rise to the hypothesis that a specific pattern ofECM degradation exists in the right and left ventricular myocardium.
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Innovations in phenotyping of mouse models in the German Mouse Clinic
Helmut Fuchs,Valerie Gailus-Durner,Susanne Neschen,Thure Adler,Luciana Caminha Afonso,Juan Antonio Aguilar-Pimentel,Lore Becker,Alexander Bohla,Julia Calzada-Wack,Christian M. Cohrs,Anna Dewert,Barbara Fridrich,Lillian Garrett,Lisa Glasl,Alexander Götz,Wolfgang Hans,Sabine M. Hölter,Marion Horsch,Anja Hurt,Eva Janas,Dirk Janik,Melanie Kahle,Martin Kistler,Tanja Klein-Rodewald,Christoph Lengger,Tonia Ludwig,Holger Maier,Susan Marschall,Kateryna Micklich,Gabriele Möller,Beatrix Naton,Cornelia Prehn,Oliver Puk,Ildiko Racz,Michael Räß,Birgit Rathkolb,Jan Rozman,Markus F. Scheerer,Evelyn Schiller,Anja Schrewe,Ralph Steinkamp,Claudia Stöger,Minxuan Sun,Wilfried Szymczak,Irina Treise,Ingrid L. Vargas Panesso,Alexandra Vernaleken,Monja Willershäuser,Annemarie Wolff-Muscate,Ramona Zeh,Jerzy Adamski,Johannes Beckers,Raffi Bekeredjian,Dirk H. Busch,Oliver Eickelberg,Jack Favor,Jochen Graw,Heinz Höfler,Christoph Höschen,Hugo A. Katus,Martin Klingenspor,Thomas Klopstock,Frauke Neff,Markus Ollert,Holger Schulz,Tobias Stöger,Eckhard Wolf,Wolfgang Wurst,Ali Önder Yildirim,Andreas Zimmer,Martin Hrabě de Angelis +70 more
TL;DR: The German Mouse Clinic is an open-access platform for the scientific community by providing phenotypic analysis in bilateral collaborations and as a partner and driver in international large-scale biology projects (“top-down projects”).