Hugo A. Katus
Heidelberg University
1553 Papers
9.9K Citations
Hugo A. Katus is an academic researcher from Heidelberg University. The author has contributed to research in topics: Medicine & Myocardial infarction. The author has an hindex of 107, co-authored 1496 publications. Previous affiliations of Hugo A. Katus include University Hospital Heidelberg.
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Papers
Accuracy of 0/1-hour algorithm for diagnosis of MI in the elderly: mono-dimensional optimization of troponin cut-offs for individual confounders or precision medicine?
Mehrshad Vafaie,Hugo A. Katus +1 more
TL;DR: The 2015 European Society of Cardiology (ESC) guidelines on non-ST-elevation acute coronary syndrome (NSTE-ACS) recommend the use of a 0/1-h algorithm for earlier diagnosis of MI, if hsTn assays implementing validated algorithms are available, and the performance of a secondary modification of the already optimized decision cut-offs is evaluated.
Cloning and characterization of zebrafish K2P13.1 (THIK-1) two-pore-domain K+ channels.
Ingo Staudacher,Sebastian Seehausen,Jakob Gierten,Claudius Illg,Patrick A. Schweizer,Hugo A. Katus,Dierk Thomas,Dierk Thomas +7 more
TL;DR: Zebrafish may be used as in vivo model for the assessment of physiology and therapeutic significance of K2P13.1.1 channels and their human orthologs exhibit structural and regulatory similarities.
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Steady‐state equilibrium phase inversion recovery ON‐resonant water suppression (IRON) MR angiography in conjunction with superparamagnetic nanoparticles. A robust technique for imaging within a wide range of contrast agent dosages
Gitsios Gitsioudis,Matthias Stuber,Ingolf Arend,Moritz Thomas,Jing Yu,T. Hilbel,Evangelos Giannitsis,Hugo A. Katus,Grigorios Korosoglou +8 more
TL;DR: To investigate the ability of inversion recovery ON‐resonant water suppression (IRON) in conjunction with P904 (superparamagnetic nanoparticles which consisting of a maghemite core coated with a low‐molecular‐weight amino‐alcohol derivative of glucose) to perform steady‐state equilibrium phase MR angiography (MRA) over a wide dose range.
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SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy
Jes-Niels Boeckel,Maximilian Möbius-Winkler,Marion Müller,Sabine Rebs,Nicole Eger,Laura Schoppe,Rewati Tappu,Karoline E. Kokot,Jasmin M Kneuer,Susanne Gaul,Diana Martins Bordalo,Alan Lai,Jan Haas,Mahsa Ghanbari,Philipp Drewe-Boss,Martin Liss,Hugo A. Katus,Uwe Ohler,Michael Gotthardt,Ulrich Laufs,Katrin Streckfuss-Bömeke,Benjamin Meder +21 more
TL;DR: In this article, the authors identified upregulation of Sam68-like Mammalian Protein 2 (SLM2) in the left ventricle of dilated cardiomyopathy (DCM) patients.
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Cardiac Effects of Attenuating Gsα - Dependent Signaling
Marcus R. Streit,Celine S. Weiss,Sören Meyer,Marco Ochs,Marco Hagenmueller,Johannes Riffel,Sebastian J. Buss,Thomas Heger,Hugo A. Katus,Stefan E. Hardt +9 more
TL;DR: Overexpression of a dominant negative mutant of Gsα leads to decreased β-adrenergic responsiveness and is protective against isoproterenol-induced hypertrophy, providing novel insights into β- adrenergic signal transduction and its modulation in myocardial overload and failure.