Huangyang Meng
Nanjing Medical University
21 Papers
Huangyang Meng is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 6, co-authored 13 publications.
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Papers
ALKBH5-HOXA10 loop-mediated JAK2 m6A demethylation and cisplatin resistance in epithelial ovarian cancer
Sipei Nie,Lin Zhang,Jinhui Liu,Yicong Wan,Yi Jiang,Jing Yang,Rui Sun,Xiaolling Ma,Guodong Sun,Huangyang Meng,Mengting Xu,Wenjun Cheng +11 more
TL;DR: Investigation of the role of AlkB homolog 5 in platinum-resistant EOC showed that JAK2 is an m6A-modified gene targeted by ALKBH5, and inhibition of the expression of the AL KBH5-HOXA10 loop maybe a potential strategy to overcome platinum resistance in EOC.
Identification of a prognostic signature of epithelial ovarian cancer based on tumor immune microenvironment exploration
Jinhui Liu,Huangyang Meng,Sipei Nie,Ying Sun,pinping jiang,Siyue Li,Jing Yang,Rui Sun,Wenjun Cheng +8 more
TL;DR: The low-risk group was found with higher immunophenoscore and distinct mutation signatures compared with the high- risk group, and may shed light on the development of novel immune biomarkers and target therapy of EOC.
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Exploration of a novel prognostic risk signatures and immune checkpoint molecules in endometrial carcinoma microenvironment.
Jinhui Liu,Sipei Nie,Zhipeng Wu,Yi Jiang,Yicong Wan,Siyue Li,Huangyang Meng,Shulin Zhou,Wenjun Cheng +8 more
TL;DR: Both the expression and immunophenoscore of immune checkpoints PD-1, CTLA4, PD-L1 andPD-L2 increased significantly in low-risk group and may provide new ideas for novel biomarkers and immunotherapy targets in EC.
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Identification of Potential Biomarkers in Association With Progression and Prognosis in Epithelial Ovarian Cancer by Integrated Bioinformatics Analysis.
Jinhui Liu,Huangyang Meng,Siyue Li,Yujie Shen,Hui Wang,Wu Shan,Jiangnan Qiu,Jie Zhang,Wenjun Cheng +8 more
TL;DR: The univariate and multivariate Cox proportional hazards regression showed that ZWINT was independent prognostic indictor among EOC patients and genes and pathways discovered in the above studies may open a new direction for EOC treatment.
Upregulated LINC00565 Accelerates Ovarian Cancer Progression By Targeting GAS6.
Mi Gong,Chengyan Luo,Huangyang Meng,Siyue Li,Sipei Nie,Yi Jiang,Yicong Wan,Huijian Li,Wenjun Cheng +8 more
TL;DR: It is discovered that LINC00565, a novel lncRNA, was highly expressed in ovarian cancer (OC), and expression level was negatively associated with outcomes of OC patients and was closely correlated to tumor size, FIGO stage, but not related to other clinical features.