7 Papers
5 Citations
Huan Yu is an academic researcher from Zhejiang Chinese Medical University. The author has contributed to research in topics: Osteoarthritis & Cartilage. The author has an hindex of 3, co-authored 7 publications.
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Papers
Loganin ameliorates cartilage degeneration and osteoarthritis development in an osteoarthritis mouse model through inhibition of NF-κB activity and pyroptosis in chondrocytes
Jia-Ming Hu,Jin-Yi Zhou,Jin-Ting Wu,Quan Chen,Weibin Du,Fangda Fu,Huan Yu,Sai Yao,Hongting Jin,Peijian Tong,Di Chen,Chengliang Wu,Hongfeng Ruan +12 more
TL;DR: Results uncovered that loganin inhibits NF-κB signaling and attenuates cartilage matrix catabolism and pyroptosis of chondrocytes in articular cartilage and may serve as a potential therapeutic agent for OA treatment.
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Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling.
Huan Yu,Sai Yao,Chengchong Zhou,Fangda Fu,Huan Luo,Weibin Du,Hongting Jin,Peijian Tong,Di Chen,Chengliang Wu,Hongfeng Ruan,Hongfeng Ruan +11 more
TL;DR: Morroniside was protective against cartilage matrix degradation and reduced DMM-induced chondrocyte pyroptosis and apoptosis by the inhibition of NF-κB signaling and attenuated the progression of OA in mice.
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TGF-β/Smad2 signalling regulates enchondral bone formation of Gli1 + periosteal cells during fracture healing
Chenjie Xia,Chenjie Xia,Qinwen Ge,Liang Fang,Huan Yu,Zhen Zou,Peng Zhang,Shuaijie Lv,Peijian Tong,Luwei Xiao,Di Chen,Pinger Wang,Hongting Jin +12 more
TL;DR: The aim of this study was to investigate whether Gli1‐CreERT2 can identify a population of murine periosteal progenitor cells and the role of TGF‐β signalling on fracture healing.
32
Biomechanical, histologic, and molecular characteristics of graft-tunnel healing in a murine modified ACL reconstruction model.
Huan Yu,Fangda Fu,Sai Yao,Huan Luo,Taotao Xu,Hongting Jin,Peijian Tong,Di Chen,Di Chen,Chengliang Wu,Hongfeng Ruan,Hongfeng Ruan +11 more
TL;DR: A metal-free, reproducible and reliable mouse model of ACLR compared to the unmodified ACLR procedure is introduced and the expression pattern of key molecules in Ihh signaling during the graft healing process is characterized.
11
Expression Profile Analysis of Differentially Expressed Circular RNAs in Steroid-Induced Osteonecrosis of the Femoral Head
TL;DR: This study provides a new and fundamental circRNA profile of SONFH and a theoretical basis for further studies on the functions of circRNAs in SonFH.