Hua Jiang
University of Texas at Austin
18 Papers
78 Citations
Hua Jiang is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 5 publications.
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Papers
The role of protein-protein interactions in the assembly of the presynaptic filament for T4 homologous recombination.
TL;DR: It is found that interactions between the uvsY protein and the C terminus of the gene 32 protein are required to load UvsY onto gene 32protein-covered DNA.
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Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
Han-Hui Ma,Yingying Guo,Haoneng Tang,Chien Te K. Tseng,Lei Wang,Huifang Zong,Zhenyu Wang,Yang He,Yunsong Chang,Shusheng Wang,Haiqiu Huang,Yong Ke,Min‐Shung Wu,Yuanyuan Zhang,Aleksandra Drelich,Kempaiah Rayavara Kempaiah,Bi Hung Peng,Ailin Wang,KaiYong Yang,H. Yin,Junjun Liu,Yali Yue,Wenbo Xu,Shuangli Zhu,Tianjiao Ji,Xiaoju Zhang,Ziqi Wang,Gang Li,Guang-Mei Liu,Jingjing Song,Li Mu,ZongShang Xiang,Z L Song,Hua Li Chen,Yanlin Bian,Baohong Zhang,Hui Chen,Jia-Wen Zhang,Yu-Jou Liao,Li Zhang,Liu Yang,Yi Chen,J. Gilly,Xiaodong Xiao,Lei Han,Hua Jiang,Yu Xie,Qiang Zhou,Jian-Ming Zhu +48 more
TL;DR: In this article , a monoclonal antibody, 2G1, was developed to neutralize all current SARS-CoV-2 variants and has surprising tolerance to mutations adjacent to or within its interaction epitope.
Tumour inhibitory activity on pancreatic cancer by bispecific nanobody targeting PD-L1 and CXCR4
Shuai Hao,Shuyi Xu,Liangzhu Li,Yaxian Li,Meiqi Zhao,Junsheng Chen,Shunying Zhu,Yu Xie,Hua Jiang,Jian-Ming Zhu,Min‐Shung Wu +10 more
TL;DR: In this paper , a bispecific nanobody was designed and constructed with bi-targeting on PD-L1 and CXCR4, which inhibited CXCL12-induced Jurkat cell migration.
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Homology Dependence of UvsX Protein-catalyzed Joint Molecule Formation
TL;DR: The efficiency of UvsX protein-mediated joint molecule formation between supercoiled duplex DNA and oligonucleotides is shown to have a sharp dependence on the degree of homology, with an intrinsic homology requirement for the formation of stable joint molecules.
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The gene 32 single-stranded DNA-binding protein is not bound stably to the phage T4 presynaptic filament.
TL;DR: It is demonstrated that a well-defined series of events involving multiple protein-DNA and protein-protein interactions is required to mediate a transition from an initial gene 32-DNA complex to a mature presynaptic filament in which the UvsX and UvsY proteins are in contact with the DNA and each other, while most or all of the gene 32 protein is removed from the complex.
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