Horst Przuntek
Ruhr University Bochum
263 Papers
2.9K Citations
Horst Przuntek is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Parkinson's disease & Medicine. The author has an hindex of 54, co-authored 263 publications. Previous affiliations of Horst Przuntek include University of Würzburg & Schering AG.
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Papers
Diagnostic staging of Parkinson's disease: conceptual aspects.
TL;DR: Earlier premotor diagnosis of PD will enable more convincing future results on the therapeutic efficacy of neuroprotective compounds and attention should be given to diseases of the gastrointestinal tract and psychosomatic disorders, all of which, if not or ineffectively treated, may contribute to an enhanced vulnerability for PD.
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Genetic background of apparently idiopathic sporadic cerebellar ataxia
Ludger Schöls,Sandra Szymanski,Sören Peters,Horst Przuntek,Jörg T. Epplen,Cornelia Hardt,Olaf Riess +6 more
TL;DR: The genetic basis in 19% of apparently idiopathic ataxia patients has revealed the most common Friedreich mutation, and SCA6 is the most frequent mutation in late onset cerebellar atAXia.
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Spinocerebellar Ataxia Type 2: Genotype and Phenotype in German Kindreds
Ludger Schöls,Suzana Gispert,Matthias Vorgerd,Ana Maria Menezes Vieira-Saecker,Peter Blanke,Georg Auburger,Georgios Amoiridis,Saskia H. Meves,Jörg T. Epplen,Horst Przuntek,Stefan M. Pulst,Olaf Riess +11 more
TL;DR: Investigation of German families of German ancestry with ADCA and patients with sporadic ataxia for the SCA2 mutation found expanded alleles were unstable during meiosis; paternal transmission especially caused significant anticipation of onset up to 26 years earlier.
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Impaired gastric emptying of a solid test meal in patients with Parkinson's disease using 13C-sodium octanoate breath test.
Oliver Goetze,Joerg Wieczorek,Thomas Mueller,Horst Przuntek,Wolfgang E. Schmidt,Dirk Woitalla +5 more
TL;DR: The OBT detects a significant delay in gastric emptying of a solid test meal in patients with Parkinson's disease and is associated with disease severity.
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SELEDO: a 5‐y‐ear long‐term trial on the effect of selegiline in early parkinsonian patients treated with levodopa
Horst Przuntek,B. Conrad,J. Dichgans,P.H. Kraus,P. Krauseneck,G. Pergande,U. Rinne,Klaus Schimrigk,J. Schnitker,H.P. Vogel +9 more
TL;DR: The SELEDO (from selegiline plus levodopa) study was carried out as a randomized, prospective, placebo‐controlled, double‐blind, multicenter long‐term, 5‐y‐ear trial to evaluate the possible advantages of combining selegILine and levodOPA in the early treatment of Parkinson's disease.
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