Hongyang Wang
Massachusetts Eye and Ear Infirmary
14 Papers
1 Citations
Hongyang Wang is an academic researcher from Massachusetts Eye and Ear Infirmary. The author has contributed to research in topics: Medicine & Hearing loss. The author has an hindex of 2, co-authored 2 publications. Previous affiliations of Hongyang Wang include Chinese Ministry of Education & Chinese PLA General Hospital.
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Papers
Conductive Nerve Guidance Conduits Based on Morpho Butterfly Wings for Peripheral Nerve Repair.
Yangnan Hu,Zhuoyue Chen,Hongyang Wang,Jiahui Guo,Jiaying Cai,Xiaoyan Chen,Hao Wei,Jieyu Qi,Qiuju Wang,Huisheng Liu,Yuanjin Zhao,Renjie Chai +11 more
TL;DR: Inspired by the physiological structures of peripheral nerves, a conductive topological scaffold for nerve repair is presented by modifying Morpho butterfly wing with reduced graphene oxide (rGO) nanosheets and methacrylated gelatin (GelMA) hydrogel encapsulated brain-derived neurotrophic factor (BDNF) and electrically conductive NGCs based on the rGO/BDNF/Gelma-integrated Morpho Butterfly wing are demonstrated.
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Sudden sensorineural hearing loss as the initial symptom in patients with acoustic neuroma
TL;DR: Hearing recovery for SSNHL does not exclude the presence of AN, and all patients initially diagnosed with SSN NHL should undergo MRI and ABR to prevent misdiagnosis and delays in potential treatment.
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Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation
Huang Wang,Haibo Du,Rui Ren,Tingting Du,Lin Lin,Zhe Feng,Dange Zhao,Xiaoxi Wei,Xiaoyan Zhai,Hongyang Wang,Tingting Dong,Jin-peng Sun,Hao Wu,Zhigang Xu,Qing Lu +14 more
TL;DR: In this paper , Li et al. showed that liquid-liquid phase separation (LLPS) mediates ankle link complex formation, providing essential clues for understanding the pathogenesis of deafness.
Impaired AIF-CHCHD4 interaction and mitochondrial calcium overload contribute to auditory neuropathy spectrum disorder in patient-iPSC-derived neurons with AIFM1 variant
Yue Qiu,Hongyang Wang,Mingjie Fan,Huaye Pan,Jing Guan,Yangwei Jiang,Zexiao Jia,Kaiwen Wu,Hui Zhou,Qianqian Zhuang,Zhaoying Lei,Xue Ding,Huajian Cai,Yufei Dong,Le-Qin Yan,Aifu Lin,Yong Fu,Dong Xing Zhang,Qingfeng Yan,Qiuju Wang +19 more
TL;DR: In this article , the authors demonstrated that the AIFM1 variant is one of the molecular bases of auditory neuropathy spectrum disorder (ANSD) and showed that correction of this variant significantly restored the structure and function of AIF, further improving the physiological state of patient-specific iPSC-derived neurons.
Generation of a gene corrected human isogenic iPSC line (CPGHi001-A-1) from a hearing loss patient with the TMC1 p.M418K mutation using CRISPR/Cas9.
TL;DR: In this paper , the TMC1 p.1253 T > A (p.M418K) mutation is homologous to that in Beethoven mice, which may induce autosomal dominant non-syndromic progressive hearing loss.
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