Hongyan Lv
Northeast Forestry University
6 Papers
29 Citations
Hongyan Lv is an academic researcher from Northeast Forestry University. The author has contributed to research in topics: Camptothecin & Chemistry. The author has an hindex of 3, co-authored 3 publications.
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Papers
Anti-proliferative and pro-apoptotic effect of CPT13, a novel camptothecin analog, on human colon cancer HCT8 cell line.
Li-Min Wang,Qingyong Li,Yuangang Zu,Yu-Jie Fu,Liyan Chen,Hongyan Lv,Li-Ping Yao,Shougang Jiang +7 more
TL;DR: The results suggest that CPT13 appears to be a potent drug against human colon cancer via induction of apoptosis and may be used as an alternative drug to therapy cancer.
31
N-trimethyl chitosan coated targeting nanoparticles improve the oral bioavailability and antioxidant activity of vitexin.
TL;DR: In this article , the authors designed vitexin loaded bilayer nanoparticles by the assembly of soybean peptides and the coating of goblet cell targeting peptide CSKSSDYQC (CSK) coupled N-trimethyl chitosan (TMC), to improve the bioavailability of VITExin.
31
Polyphenolic Extracts of Coffee Cherry Husks Alleviated Colitis-Induced Neural Inflammation via NF-κB Signaling Regulation and Gut Microbiota Modification.
TL;DR: The results indicated that CCHP administration alleviated the histological changes of DSS-induced colitis in mice and downregulated the mRNA level of TNF-α, IL-1β,IL-6 and Cox-2, and inhibited the activation of microglia and suppressed neural inflammation in the brain.
17
Cytotoxicity and topo I targeting activity of substituted 10--nitrogenous heterocyclic aromatic group derivatives of SN-38.
TL;DR: Ethyl in the 7-position of these compounds can increase the cytotoxicity and inhibitory activity to topo I compared with corresponding pyridine salts CPT derivatives and simultaneously maintain good water solubility, consistent with the SAR of CPT.
15
Fabrication of diosmin loaded food-grade bilayer nanoparticles with modified chitosan and soy peptides and antioxidant properties examination
Sen Li,Tong Guan,Hongyan Lv,Yuwei Cai,Wanqing Cao,Ze Zhang,Hongdong Song,Hong-wei Cao,Xiao Guan +8 more
- 01 Feb 2024
TL;DR: Researchers fabricated diosmin-loaded bilayer nanoparticles using modified chitosan and soy peptides, enhancing its oral bioavailability and antioxidant properties, with promising results in vitro and in vivo, suggesting a potential therapeutic application.