Hong Liang
Guangxi Normal University
456 Papers
2.3K Citations
Hong Liang is an academic researcher from Guangxi Normal University. The author has contributed to research in topics: Chemistry & Apoptosis. The author has an hindex of 46, co-authored 386 publications. Previous affiliations of Hong Liang include Nankai University & Nanjing University.
Chat about Author
Papers
Anticancer Function and ROS-Mediated Multi-Targeting Anticancer Mechanisms of Copper (II) 2-hydroxy-1-naphthaldehyde Complexes.
TL;DR: The synthesized Cu2+ complexes established ROS-mediated targeting of multiple cell signaling pathways as a fabulous route for the inhibition of cancer cell growth.
31
Chemodynamic therapy agents Cu(II) complexes of quinoline derivatives induced ER stress and mitochondria-mediated apoptosis in SK-OV-3 cells.
TL;DR: In this article, three quinoline derivatives were synthesized and characterized as cancer chemodynamic therapy agents, and the complexes were heavily taken up by cells and reacted with cellular glutathione (GSH) to reduce Cu2+ to Fenton-like Cu+, which catalyzed endogenous H2O2 to produce the highly toxic hydroxyl radicals (•OH) to kill cancer cells.
31
One-Step Fabrication of a Multifunctional Aggregation-Induced Emission Nanoaggregate for Targeted Cell Imaging and Enzyme-Triggered Cancer Chemotherapy
TL;DR: HA endowed the QA-TPE/HA nanoaggregate both good biocompatibility and hysteretic chemotherapy activity, which were achieved by controlling the release of QE using the endogenous HAase in CD44 receptor-mediated cancer cells.
30
Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth.
Rongtao Huang,Zhaoyang Ding,Bang-Ping Jiang,Luo Zilan,Ting Chen,Zhengxi Guo,Shichen Ji,Hong Liang,Xing-Can Shen +8 more
TL;DR: Further combination with the cytotoxic T-lymphocyte-associated protein 4 checkpoint blockade is reported to effectively eliminate the primary tumor and inhibit distant tumor growth via the abscopal effect of antitumor immune responses, prolonging the survival.
30
Recent Advances in Asialoglycoprotein Receptor and Glycyrrhetinic Acid Receptor-Mediated and/or pH-Responsive Hepatocellular Carcinoma- Targeted Drug Delivery.
TL;DR: The multifunctional DDS may prolong systemic circulation, continuously release drugs, increase drugs tumor accumulation at targeted site, enhance anticancer effect, and reduce side effects both in vitro or vivo.
30