Hirotaka Watada
Juntendo University
562 Papers
2.6K Citations
Hirotaka Watada is an academic researcher from Juntendo University. The author has contributed to research in topics: Diabetes mellitus & Medicine. The author has an hindex of 67, co-authored 460 publications. Previous affiliations of Hirotaka Watada include Osaka University & University of California, San Francisco.
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Papers
Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis.
Hirotsugu Uzawa,Daisuke Kohno,Tomoaki Koga,Tomoaki Koga,Tsutomu Sasaki,Tsutomu Sasaki,Ayako Fukunaka,Toshiaki Okuno,Airi Jo-Watanabe,Saiko Kazuno,Takeshi Miyatsuka,Tadahiro Kitamura,Yoshio Fujitani,Hirotaka Watada,Kazuko Saeki,Takehiko Yokomizo +15 more
TL;DR: It is indicated that LTA4H mediates the diet‐induced obesity by reducing catecholamine and thyroid hormone secretion.
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Association of T2 relaxation time determined by magnetic resonance imaging and intramyocellular lipid content of the soleus muscle in healthy subjects
Yuko Sakurai,Yoshifumi Tamura,Kageumi Takeno,Fumihiko Sato,Yoshio Fujitani,Takahisa Hirose,Ryuzo Kawamori,Hirotaka Watada +7 more
TL;DR: The result suggests the possibility that T2 relaxation time of the soleus muscle can be used to estimate IMCL in a clinical setting and investigates the association between T1 and T1 relaxation times, determined by MR imaging, and IMCL measured by 1H‐MRS in the Soleus and tibialis anterior muscles of 15 healthy male subjects.
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Evidence-based comparison of glucagon-like peptide receptor agonists and sodium-glucose cotransporter 2 inhibitors.
TL;DR: In vitro and animal studies have demonstrated that hyperglycemia elicits harmful effects on the cells that comprise the vasculature or those that are involved in the progression of atherosclerosis through various mechanisms such increased oxidative stress, advanced glycation end-product signaling, and protein kinase C activation.
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Effect of patient characteristics on the efficacy and safety of imeglimin monotherapy in Japanese patients with type 2 diabetes mellitus: A post-hoc analysis of two randomized, placebo-controlled trials.
TL;DR: In this article , the efficacy and safety of IMGlimin 1,000 mg twice daily (BID) monotherapy in type 2 diabetes mellitus patients according to demographic and clinical characteristics were evaluated.
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Effects of linagliptin vs. voglibose on daily glucose excursions during continuous glucose monitoring of Japanese type 2 diabetes patients (L-CGM): A randomized, open-label, two-arm, parallel comparative trial.
Hiroaki Satoh,Hiroaki Satoh,Tetsuya Ohira,C. Moriya,C. Moriya,Ikuo Inoue,S. Kuribayashi,H. Seino,Hiroyuki Hirai,Toru Hiyoshi,Hirotaka Watada +10 more
TL;DR: The present randomized prospective multicentre study into the effects of linagliptin on daily glucose excursions on CGM in type 2 diabetes mellitus (T2DM) patients was conducted to investigate whether linaglisptin was superior to voglibose in reducing glucose excursion in patients with T2DM.
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