Hiroshi Yotsuyanagi
University of Tokyo
257 Papers
1.6K Citations
Hiroshi Yotsuyanagi is an academic researcher from University of Tokyo. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 37, co-authored 201 publications. Previous affiliations of Hiroshi Yotsuyanagi include St. Marianna University School of Medicine & Institute of Medical Science.
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Papers
Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen
Ayaka Washizaki,Asako Murayama,Megumi Murata,Tomoko Kiyohara,Keigo Yato,Norie Yamada,Hussein H. Aly,Tomohisa Tanaka,Kohji Moriishi,Hironori Nishitsuji,Kunitada Shimotohno,Yasumasa Yayoigaoka Cho Goh,Ken Ishii,Hiroshi Yotsuyanagi,Masami Muramatsu,Koji Ishii,Yoshimasa Takahashi,Ryosuke O. Suzuki,Hirofumi Akari,Takanobu Kato +19 more
TL;DR: Yeast-derived large-HBsAg is immunized into rhesus macaques, and the neutralizing activities of the induced antibodies are compared with those of the current HB vaccine as mentioned in this paper .
Machine learning for individualized prediction of hepatocellular carcinoma development after the eradication of hepatitis C virus with antivirals.
Tatsuya Minami,Masaya Sato,Hidenori Toyoda,Satoshi Yasuda,Tomoharu Yamada,Takuma Nakatsuka,Kenichiro Enooku,Hayato Nakagawa,H. Fujinaga,Masashi Izumiya,Yasuo Tanaka,Motoyuki Otsuka,Takamasa Ohki,Masahiro Arai,Yoshinari Asaoka,Atsushi Tanaka,K. Yasuda,Hideaki Miura,Itsuro Ogata,Toshiro Kamoshida,Kazuaki Inoue,Ryo Nakagomi,Masatoshi Akamatsu,Hiroshi Mitsui,Hajime Fujie,Keiji Ogura,Koji Uchino,Hideo Yoshida,Kazuyuki Hanajiri,Tomonori Wada,K. Kurai,Hisato Maekawa,Y. Kondo,Shuntaro Obi,Takuma Teratani,Naohiko Masaki,K. Nagashima,Takashi Ishikawa,Naoya Kato,Hiroshi Yotsuyanagi,Kyoji Moriya,Takashi Kumada,Mitsuhiro Fujishiro,K. Koike,Ryosuke Tateishi +44 more
TL;DR: A novel prediction model for HCC occurrence in patients after hepatitis C virus eradication was developed and externally validated with good predictive performance for the risk of HCC after an SVR and could provide a personalized surveillance system.
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Virological features of hepatitis B virus‐associated nephropathy in Japan
Atsunori Kusakabe,Yasuhito Tanaka,Fuat Kurbanov,Kenji Goto,Hitoshi Tajiri,Jun Murakami,Chiaki Okuse,Hiroshi Yotsuyanagi,Takashi Joh,Masashi Mizokami +9 more
TL;DR: Hepatitis B virus (HBV)‐associated nephropathy is considered as an immune‐mediated disorder which is dependent on interactions between viral, host, and environmental factors, and little relationship between HBV gene mutations and the development of HBV‐ associated nephrophobia was observed.
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English version of Japanese guidance for use of biologics for psoriasis (the 2022 version)
Hidehisa Saeki,Tomotaka Mabuchi,Akihiko Asahina,Masatoshi Abe,Atsuyuki Igarashi,Shinichi Imafuku,Yukari Okubo,Mayumi Komine,Shigetoshi Sano,Hideshi Torii,Akimichi Morita,Hiroshi Yotsuyanagi,Akira Watanabe,Mamitaro Ohtsuki +13 more
TL;DR: The English version of Japanese guidance for use of biologics for psoriasis (the 2022 version) was published in this article . But it is not yet available in the Japanese market.
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Noninvasive diagnostic criteria for nonalcoholic steatohepatitis based on gene expression levels in peripheral blood mononuclear cells
Akira Kado,Takeya Tsutsumi,Kenichiro Enooku,Hidetaka Fujinaga,Kazuhiko Ikeuchi,Kazuya Okushin,Kyoji Moriya,Hiroshi Yotsuyanagi,Kazuhiko Koike +8 more
TL;DR: Expression levels of the cytokine- and chemokine-encoding genes in PBMCs were positively correlated with ballooning, suggesting their utility for the diagnosis of NASH, and a scoring system to discriminate NASH from NAFL was developed.
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