Hiroshi Kanamaru
Kyoto University
8 Papers
143 Citations
Hiroshi Kanamaru is an academic researcher from Kyoto University. The author has contributed to research in topics: Nordihydroguaiaretic acid & Renal cell carcinoma. The author has an hindex of 4, co-authored 8 publications. Previous affiliations of Hiroshi Kanamaru include Laboratory of Molecular Biology.
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Papers
Measurement of multidrug-resistance messenger RNA in urogenital cancers; elevated expression in renal cell carcinoma is associated with intrinsic drug resistance.
Yoshiyuki Kakehi,Yoshiyuki Kakehi,Hiroshi Kanamaru,Hiroshi Kanamaru,Osamu Yoshida,Osamu Yoshida,Hiroaki Ohkubo,Hiroaki Ohkubo,Shigetada Nakanishi,Shigetada Nakanishi,Michael M. Gottesman,Michael M. Gottesman,Ira H. Pastan,Ira H. Pastan +13 more
TL;DR: The results suggest that the high MDR1 RNA levels in renal cell carcinomas are associated with intrinsic multidrug-resistance.
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MDR1 RNA Levels in Human Renal Cell Carcinomas: Correlation With Grade and Prediction of Reversal of Doxorubicin Resistance by Quinidine in Tumor Explants
Hiroshi Kanamaru,Yoshiyuki Kakehi,Osamu Yoshida,Shigetada Nakanishi,Ira H. Pastan,Michael M. Gottesman +5 more
TL;DR: Results suggest that P-glycoprotein is active in the natural resistance of RCCs to doxorubicin (ADR), and enhancement by quinidine of sensitivity to ADR was also observed in the established RCC cell lines in which MDR1 RNA levels were high.
121
Anti-promoting effect of nordihydroguaiaretic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine and sodium saccharin-induced rat urinary bladder carcinogenesis.
Akinori Yu,Takayuki Hashimura,Yasunori Nishio,Hiroshi Kanamaru,Shigeki Fukuzawa,Osamu Yoshida +5 more
TL;DR: It is suggested that NDGA has an anti‐tumor‐promoting effect on rat bladder carcinogenesis and the number of PN hyperplasic foci per 10 cm of basement membrane in rats treated with SS plus NDGA was lower than that in the group treated withSS alone.
17
Soft agar colony formation of bladder cells during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine and application to detection of bladder cancer promoters.
TL;DR: In this paper, N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN) was given to male Fischer 344 rats at a dose of 0.05% in drinking water for 2, 4, 6 and 12 weeks, and double soft agar colony formation of the uroepithelial cells was determined periodically, during and after this administration.
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•Journal Article
Afferent nipple valve malfunction as a late complication of the Kock continent ileal reservoir
Yoichi Arai,Tadashi Matsuda,Shuichi Hida,Yoshiyuki Okada,Tadeuchi H,Osamu Yoshida,Kihara Y,Seiji Moroi,Shirahase T,Hiroshi Kanamaru +9 more
TL;DR: The results suggest that the use of nonabsorbable material as a collar and peristaltic direction of the afferent limb are mainly involved in the complications of the Afferent nipple.
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