Hiroko Sashio
Hyogo College of Medicine
6 Papers
100 Citations
Hiroko Sashio is an academic researcher from Hyogo College of Medicine. The author has contributed to research in topics: Helicobacter pylori & Single-nucleotide polymorphism. The author has an hindex of 5, co-authored 6 publications.
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Papers
IL18 polymorphism is associated with an increased risk of Crohn's disease
Kazuo Tamura,Yoshihiro Fukuda,Hiroko Sashio,Naohisa Takeda,Hiroko Bamba,Tadashi Kosaka,Shin Fukui,Koji Sawada,K. Tamura,Masamichi Satomi,Takahiro Yamada,Takehira Yamamura,Yoshihiro Yamamoto,Jun-ichi Furuyama,Haruki Okamura,Takashi Shimoyama +15 more
TL;DR: IL18 is probably one of several genes that determine susceptibility to Crohn’s disease, and a novel single nucleotide polymorphism (SNP) was identified as TCA/ TCC at codon 35 of IL18 may increase the risk for Crohn's disease, especially in females.
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Influence of truth disclosure on quality of life in cancer patients
Noritoshi Tanida,Noriyasu Yamamoto,Hiroko Sashio,Yoshihiro Nakamura,Takashi Sakagami,Yukio Sawada,Takashi Shimoyama +6 more
TL;DR: Incurability of cancer, not truth disclosure, negatively affects patients' QOL and if sufficient supportive care is provided particularly to patients with incurable cancer, the truth could be disclosed without fear of being cruel or harming patients.
13
•Journal Article
Pathological changes in glandular stomach of Helicobacter pylori-infected Mongolian gerbil model.
Yukio Sawada,Kuroda Y,Hiroko Sashio,Noriyasu Yamamoto,Yasushi Tonokatsu,Takashi Sakagami,Yoshihiro Fukuda,Takashi Shimoyama,Takashi Nishigami,Kunio Uematsu +9 more
TL;DR: Some histological findings were similar to those in humans, but the chronic inflammation in the gerbils was present mainly in the deep mucosa and submucosa, and this appears to be a good animal model for H. pylori-associated gastric diseases and it may be useful for investigating the pathogenesis of H.pylori infection.
9
Pathologic changes in the glandular stomach and duodenum in an H. pylori-infected Mongolian gerbil model.
Yukio Sawada,Hiroko Sashio,Noriyasu Yamamoto,Nobuyuki Hida,Hiromitsu Akashi,Yasushi Tonokatsu,Takashi Sakagami,Yoshihiro Fukuda,Takashi Shimoyama,Takashi Nishigami,Kunio Uematsu +10 more
TL;DR: A Helicobacter pylori-infected Mongolian gerbil model following Hirayama's method is established and some histologic findings were similar to those in humans, but inflammation occurred mainly in the deep mucosa and submucosa.
7
Mongolian Gerbils Model
Takashi Shimoyama,Takashi Sakagami,Noriyasu Yamamoto,Yukio Sawada,Yoshihiro Fukuda,Noritoshi Tanida,Hiroko Sashio,Kazuo Tamura +7 more
- 01 Jan 2002
TL;DR: This chapter examines the serial changes in gastric lesions including gastric carcinogenesis in this model using an animal model infected with H. pylori using Mongolian gerbils.