Hideki Ohno
Kanazawa University
9 Papers
171 Citations
Hideki Ohno is an academic researcher from Kanazawa University. The author has contributed to research in topics: Gene & Binding site. The author has an hindex of 7, co-authored 9 publications.
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Papers
Expression of interferon alpha/beta receptor in the liver of chronic hepatitis C patients
Eishiro Mizukoshi,Shuichi Kaneko,Masayuki Yanagi,Hideki Ohno,Kyosuke Kaji,Shuichi Terasaki,Atsushi Shimoda,Eiki Matsushita,Kenichi Kobayashi +8 more
TL;DR: The expression level in patients with chronic hepatitis was significantly higher than that in normal livers and in cirrhotic livers, suggesting that the expression of IFN α/β receptor mRNA may be one of the host factors influencing the response to IFN therapy.
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Upregulation of type I interferon receptor by IFN-gamma.
Eishiro Mizukoshi,Shuichi Kaneko,Masayuki Yanagi,Hideki Ohno,Eiki Matsushita,Kenichi Kobayashi +5 more
TL;DR: It is suggested that combined treatment with type I IFN and IFN-gamma may be more effective than that of type II IFN alone and that the upregulation of type IIFN receptor may be one of the reasons.
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Human hepatitis B virus enhancer 1 is responsive to human interleukin-6
TL;DR: Results indicate that IL‐6 increased the enhancer activity of HBV Enh1 through signal transduction pathways, indirectly involving NF‐IL6, and may control HBV X expression and viral replication in HBV infected liver.
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Human hepatitis B virus X protein augments the DNA binding of nuclear factor for IL-6 through its basic-leucine zipper domain.
TL;DR: Results indicate that HBx alters the DNA‐binding affinity of NF‐IL6 through the direct interaction between the C‐terminal domain of HBx and the basic region‐leucine zipper domain of NF-IL6.
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Cloning and characterization of the 5′-flanking region of human cytokeratin 19 gene in human cholangiocarcinoma cell line
TL;DR: This segment of the 5'-flanking region of the human cytokeratin 19 gene shows an intense transcriptional activity in the cholangioma cell line KMBC, which was about 10 times itsActivity in the osteosarcoma cell line Saos-2, which does not express cytokersatin 19.
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