Hideki Kato
Yeshiva University
5 Papers
5 Citations
Hideki Kato is an academic researcher from Yeshiva University. The author has contributed to research in topics: Wnt signaling pathway & Notch signaling pathway. The author has an hindex of 5, co-authored 5 publications. Previous affiliations of Hideki Kato include Albert Einstein College of Medicine.
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Papers
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
Bernhard Bielesz,Yasemin Sirin,Yasemin Sirin,Han Si,Thiruvur Niranjan,Antje Gruenwald,Seon-Ho Ahn,Hideki Kato,James Pullman,Manfred Gessler,Volker H. Haase,Katalin Susztak +11 more
TL;DR: It is established that epithelial injury and Notch signaling play key roles in fibrosis development and indicate that Notch blockade may be a therapeutic strategy to reduce fibrosis and ESRD development.
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival
Hideki Kato,Antje Gruenwald,Jung Hee Suh,Jeffrey H. Miner,Laura Barisoni-Thomas,Makoto Mark Taketo,Christian Faul,Sarah E. Millar,Lawrence B. Holzman,Katalin Susztak +9 more
TL;DR: Results indicate that Wnt/Ctnnb1 signaling in podocytes plays a critical role in integrating cell adhesion, motility, cell death, and differentiation and Balanced Ctnnb 1 expression is critical for glomerular filtration barrier maintenance.
189
Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function
Mariana Murea,Jun Ki Park,Shuchita Sharma,Hideki Kato,Antje Gruenwald,Thiruvur Niranjan,Han Si,David B. Thomas,James Pullman,Michal L. Melamed,Katalin Susztak +10 more
TL;DR: The results raise the possibility that Notch pathway activation is a common mechanism in the pathophysiology of a wide range of acquired renal diseases.
181
Smad1 as a Biomarker for Diabetic Nephropathy
TL;DR: To identify patients at increased risk for the development of diabetic nephropathy, considerable scientific effort has been dedicated to developing new screening and prognostic markers, and the hope is that these new biomarkers will predict theDevelopment of the disease earlier than the currently used disease marker, albuminuria.
6
Repair Problems in Podocytes: Wnt, Notch and Glomerulosclerosis
Hideki Kato,Katalin Susztak +1 more
TL;DR: The role and regulation of Wnt/Ctnnb1 and Notch signaling in podocytes is discussed, which play key roles in kidney development and epithelial cell specification.