Hidehiro Ozawa
Niigata University
91 Papers
1.2K Citations
Hidehiro Ozawa is an academic researcher from Niigata University. The author has contributed to research in topics: Bone cell & Bone remodeling. The author has an hindex of 29, co-authored 90 publications.
Chat about Author
Papers
Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor β
Keisuke Horiuchi,Norio Amizuka,Sunao Takeshita,Hiroyuki Takamatsu,Mieko Katsuura,Hidehiro Ozawa,Yoshiaki Toyama,Lynda F. Bonewald,Akira Kudo +8 more
TL;DR: Immunohistochemistry and reverse transcription‐ polymerase chain reaction analysis suggest that periostin may play a role in the recruitment and attachment of osteoblast precursors in theperiosteum.
978
Haploinsufficiency of Parathyroid Hormone-Related Peptide (PTHrP) Results in Abnormal Postnatal Bone Development
N Amizuka,Andrew C. Karaplis,Andrew C. Karaplis,Janet E. Henderson,Janet E. Henderson,Hershey Warshawsky,Mark L. Lipman,Mark L. Lipman,Yutaka Matsuki,Sadakazu Ejiri,Mikako Tanaka,Naoya Izumi,Hidehiro Ozawa,David Goltzman +13 more
TL;DR: Observation that identification of both the ligand and its N-terminal receptor in metaphyseal osteoblasts and their progenitors suggests an autocrine/paracrine role for the protein in osteoblast differentiation and/or function indicates that the skeletal effects of PTH are influenced by locally produced PTHrP.
248
Strong Static Magnetic Field Stimulates Bone Formation to a Definite Orientation In Vitro and In Vivo
Hiroko Kotani,Hiroshi Kawaguchi,Takashi Shimoaka,Masakazu Iwasaka,Shoogo Ueno,Hidehiro Ozawa,Kozo Nakamura,Kazuto Hoshi +7 more
TL;DR: It is concluded that a strong SMF has the potency not only to stimulate bone formation, but also to regulate its orientation in both in vitro and in vivo models, and is the first study to show the regulation of the orientation of adherent cells by a magnetic field.
197
Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion
N Amizuka,Janet E. Henderson,Kazuto Hoshi,Hershey Warshawsky,Hidehiro Ozawa,David Goltzman,Andrew C. Karaplis +6 more
TL;DR: Observations indicate that PTHrP plays a pivotal role in the orderly progression of chondrocytes through stages of proliferation, differentiation, and programmed cell death in the epiphyseal growth plate and may also facilitate the commitment of precursors to cells of the chONDrocytic or osteoblastic lineages.
131
Targeted disruption of cadherin-11 leads to a reduction in bone density in calvaria and long bone metaphyses.
Jitsutaro Kawaguchi,Yoshiaki Azuma,Kazuto Hoshi,Isao Kii,Sunao Takeshita,Tomohiro Ohta,Hidehiro Ozawa,Masatoshi Takeichi,Osamu Chisaka,Akira Kudo +9 more
TL;DR: Results show that absence of cadherin‐11 leads to reduced bone density in some parts of skeletons including calvaria and long bone metaphyses, and suggest that cadher in‐11 plays roles in the regulation of osteoblast differentiation and in the mineralization of the osteoid matrix.
96