HH Kwok
Hong Kong Baptist University
23 Papers
75 Citations
HH Kwok is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Angiogenesis & Ginsenoside. The author has an hindex of 12, co-authored 23 publications. Previous affiliations of HH Kwok include University of Hong Kong & Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Papers
The Melanogenesis-Inhibitory Effect and the Percutaneous Formulation of Ginsenoside Rb1
Lin Wang,Aiping Lu,Zhi-Ling Yu,Ricky N S Wong,Zhaoxiang Bian,HH Kwok,Patrick Y K Yue,Limin Zhou,Hubiao Chen,Min Xu,Zhijun Yang +10 more
TL;DR: The results showed that Rb1 inhibited melanogenesis in α-melanocyte-stimulating hormone (α-MSH)-stimulated B16 cells in a dose-dependent manner, which collectively indicated that R b1 may have skin-whitening effects and may be formulated into skin- whitening products for skin care.
An indirubin derivative, E804, exhibits potent angiosuppressive activity
Yuk-Kit Chan,HH Kwok,Lai-Sheung Chan,Kelvin Sze-Ying Leung,Jue Shi,Nai Ki Mak,Ricky N S Wong,Patrick-Ying Kit Yue +7 more
TL;DR: This study provides the first evidence that E804, a novel indirubin derivative, could more effectively inhibit angiogenesis, and with the improved anti-angiogenic potency when compared with indirUBin-3'oxime, E804 would be a new potential candidate in the treatment of angiogenic-dependent diseases.
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Role of microRNA-520h in 20(R)-ginsenoside-Rg3-mediated angiosuppression
TL;DR: This study examined the underlying mechanisms of Rg3-induced angiosuppression through modulating the miRNA expression and showed that overexpression of miR-520h could significantly suppress the EphB2 andEphB4 protein expression, proliferation, and tubulogenesis of HUVECs, and the subintestinal-vessel formation of the zebra fish.
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Ginsenoside compound K induces apoptosis in nasopharyngeal carcinoma cells via activation of apoptosis-inducing factor
Carmen Ka Man Law,HH Kwok,Po-Ying Poon,Chi-Chiu Lau,Zhi-Hong Jiang,William Chi-Shing Tai,Wendy Wen-luan Hsiao,Nai Ki Mak,Patrick Y K Yue,Ricky N S Wong +9 more
TL;DR: Four ginsenosides, 20 (S)-Rh2, compound K (CK), panaxadiol (PD) and protopanax adiol (PPD), induced apoptotic cell death in HK-1 cells in a concentration-dependent manner and could significantly inhibit tumor growth in vivo.
Cytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA Damage
TL;DR: Ginsenoside 20(S)-Rg3 can protect against BaP-induced genotoxicity in human cells, suggesting that ginseng may serve as a natural cytoprotective agent against environmental carcinogens.
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