Hervé Pelloux
Joseph Fourier University
145 Papers
853 Citations
Hervé Pelloux is an academic researcher from Joseph Fourier University. The author has contributed to research in topics: Toxoplasma gondii & Toxoplasmosis. The author has an hindex of 37, co-authored 136 publications. Previous affiliations of Hervé Pelloux include French Institute of Health and Medical Research & Centre national de la recherche scientifique.
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Papers
Genotype of 86 Toxoplasma gondii Isolates Associated with Human Congenital Toxoplasmosis, and Correlation with Clinical Findings
Daniel Ajzenberg,Nadine Cogné,Luc Paris,Marie-Hélène Bessières,Philippe Thulliez,Denis Filisetti,Hervé Pelloux,Pierre Marty,Marie-Laure Dardé +8 more
TL;DR: To study the influence of Toxoplasma gondii genotypes on the severity of human congenital toxoplasmosis (asymptomatic, benign, or severe infection or newborn or fetal death), 8 microsatellite markers were used and type II isolates were largely predominant.
496
Prevention of toxoplasmosis in transplant patients
F. Derouin,Hervé Pelloux +1 more
TL;DR: Serological screening of donors and recipients before transplantation allows the identification of patients at higher risk of toxoplasmosis, i.e. seropositive HSCT recipients and mismatched (seropos positive donor/seronegative recipients) SOT recipients.
346
A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
Laurence Braun,Marie-Pierre Brenier-Pinchart,Marie-Pierre Brenier-Pinchart,Manickam Yogavel,Aurélie Curt-Varesano,Aurélie Curt-Varesano,Rose-Laurence Curt-Bertini,Rose-Laurence Curt-Bertini,Tahir Hussain,Sylvie Kieffer-Jaquinod,Sylvie Kieffer-Jaquinod,Yohann Couté,Yohann Couté,Hervé Pelloux,Hervé Pelloux,Isabelle Tardieux,Amit Sharma,Hassan Belrhali,Alexandre Bougdour,Alexandre Bougdour,Mohamed-Ali Hakimi,Mohamed-Ali Hakimi +21 more
TL;DR: Toxoplasma gondii secretes a novel dense granule protein, GRA24, that traffics from the vacuole to the host cell nucleus where it prolongs p38a activation and correlates with proinflammatory cytokine production.
282
Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression
Alexandre Bougdour,Eric Durandau,Eric Durandau,Marie-Pierre Brenier-Pinchart,Marie-Pierre Brenier-Pinchart,Philippe Ortet,Mohamed Barakat,Sylvie Kieffer,Sylvie Kieffer,Aurélie Curt-Varesano,Aurélie Curt-Varesano,Rose-Laurence Curt-Bertini,Rose-Laurence Curt-Bertini,Olivier Bastien,Yohann Couté,Yohann Couté,Hervé Pelloux,Hervé Pelloux,Mohamed-Ali Hakimi,Mohamed-Ali Hakimi +19 more
TL;DR: This work identifies GRA16 as a dense granule protein that is exported through the PV membrane and reaches the host cell nucleus, where it positively modulates genes involved in cell-cycle progression and the p53 tumor suppressor pathway.
253
Genotype of 88 Toxoplasma gondii Isolates Associated with Toxoplasmosis in Immunocompromised Patients and Correlation with Clinical Findings
Daniel Ajzenberg,Hélène Yera,Pierre Marty,Luc Paris,Frédéric Dalle,Jean Menotti,Dominique Aubert,Jacqueline Franck,Marie-Hélène Bessières,Dorothée Quinio,Hervé Pelloux,Laurence Delhaes,N. Desbois,Philippe Thulliez,Florence Robert-Gangneux,C. Kauffmann-Lacroix,Sophie Pujol,Meja Rabodonirina,Marie-Elisabeth Bougnoux,B. Cuisenier,Chantal Duhamel,Thanh Hai Duong,Denis Filisetti,Pierre Flori,Françoise Gay-Andrieu,Francine Pratlong,Gilles Nevez,Anne Totet,Bernard Carme,Henri Bonnabau,Marie-Laure Dardé,Isabelle Villena +31 more
TL;DR: It is concluded that in immunocompromised patients, host factors are much more involved than parasite factors in patients' resistance or susceptibility to toxoplasmosis.
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