Henning Ulrich
University of São Paulo
302 Papers
1.3K Citations
Henning Ulrich is an academic researcher from University of São Paulo. The author has contributed to research in topics: Receptor & Biology. The author has an hindex of 41, co-authored 266 publications. Previous affiliations of Henning Ulrich include Jagiellonian University & Cornell University.
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Papers
Glioblastoma stem-like cells: approaches for isolation and characterization
Erika de Simone Molina,Micheli M. Pillat,Vivaldo Moura-Neto,Tamara T. Lah,Henning Ulrich +4 more
- 01 Jan 2014
TL;DR: The enrichment of GSC phenotypes in established cell lines and/or primary tumor cultures, achieved by different strategies, is reviewed, providing a comprehensive comparison of selected studies and contemplating the characterization of the plethora of variants of reported GBM population exhibiting the GSC phenotype.
Kinin-B2 Receptor Activity Determines the Differentiation Fate of Neural Stem Cells
Cleber A. Trujillo,Priscilla D. Negraes,Telma T. Schwindt,Claudiana Lameu,Cassiano Carromeu,Alysson R. Muotri,João Bosco Pesquero,Débora M. Cerqueira,Micheli M. Pillat,Hellio Danny Nóbrega de Souza,Lauro Thiago Turaça,José G. Abreu,Henning Ulrich +12 more
TL;DR: Bradykinin acts as switch for phenotype determination using an in vitro system of migrating cells, closely reflecting conditions of cortex development and providing a switch for neural fate determination and specification of neurotransmitter receptor expression.
Receptor-specific Ca2+ oscillation patterns mediated by differential regulation of P2Y purinergic receptors in rat hepatocytes
Juliana C. Corrêa-Velloso,Paula J. Bartlett,Robert Brumer,Lawrence D. Gaspers,Henning Ulrich,Andrew P. Thomas +5 more
TL;DR: In this paper, the authors used qPCR to show that rat hepatocytes express multiple purinergic P2Y and P2X receptors (R) and showed that ADP acting through P 2Y1R elicited narrow Ca2+ oscillations, whereas UTP acting through p 2Y2R elicits broad Ca2+, with composite patterns observed for ATP.
P2X7 receptor isoform B is a key drug resistance mediator for neuroblastoma
Vanessa Fernandes Arnaud-Sampaio,Carolina Bento,Talita Glaser,Elena Adinolfi,Henning Ulrich,Claudiana Lameu +5 more
TL;DR: The contributions of P2X7 receptor A and B isoforms to neuroblastoma chemoresistance are elucidated, demonstrating that the B isoform favors resistance through a combination of mechanisms involving drug efflux via MRP-type transporters, resistance to retinoids, retaining cells in a stem-like phenotype, suppression of autophagy, and EMT induction.
Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1L39R Linked Amyotrophic Lateral Sclerosis
C. S. Rajpurohit,C. S. Rajpurohit,Vivek Kumar,Arquimedes Cheffer,Arquimedes Cheffer,Danyllo Oliveira,Henning Ulrich,Oswaldo Keith Okamoto,Mayana Zatz,Uzair Ahmad Ansari,Uzair Ahmad Ansari,Vinay K. Khanna,Vinay K. Khanna,Aditya B. Pant,Aditya B. Pant +14 more
TL;DR: Perhaps for the first time, it is reported that the MN degeneration in ALS triggered by the hyper-activation of autophagy and induced apoptosis in both cell-autonomous and non-cell autonomous conditions.