Helmut Vedder
Max Planck Society
16 Papers
136 Citations
Helmut Vedder is an academic researcher from Max Planck Society. The author has contributed to research in topics: Receptor & Cytokine. The author has an hindex of 13, co-authored 16 publications. Previous affiliations of Helmut Vedder include University of Marburg.
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Papers
Sex differences in cortisol response to noxious stress.
TL;DR: Men show a larger cortisol response to a noxious stressor than women that is not attributable to sex differences in subjective pain, and the conclusion of a causal relation between larger cortisol responses and higher pain tolerance thresholds in men is tempting but yet speculative.
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Glucocorticoid and mineralocorticoid receptors in rat neocortical and hippocampal brain cells in culture: characterization and regulatory studies
TL;DR: Competition binding studies with [3H]DEX demonstrated a glucocorticoid specificity of receptor sites (relative binding affinity: RU 28362 = DEX > PROG > ALDO).
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•Journal Article
Glucocorticoid and mineralocorticoid receptors in rat neocortical and hippocampal brain cells in culture: characterization and regulatory studies
TL;DR: In this paper, the binding sites of glucocorticoid receptors were characterized in cell cultures derived from neocortical and hippocampal brain tissue from fetal (E18) rats.
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Endotoxin- and Corticotropin Releasing Hormone-Induced Release of ACTH and Cortisol
Wolfgang Schreiber,Thomas Pollmächer,Klaus Fassbender,S. Gudewill,Helmut Vedder,Klaus Wiedemann,Chris Galanos,Florian Holsboer +7 more
TL;DR: The endotoxin challenge test presented here may serve as an appropriate and safe tool to explore an individual's capacity for neuroendocrine adaptation to a bacterial stressor, thus providing information complementary to the CRH test.
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Corticotropin-releasing-hormone lacks analgesic properties: an experimental study in humans, using non-inflammatory pain.
Stefan Lautenbacher,Stephan Roscher,Gabi Kohl,Helmut Vedder,Helmut Vedder,Jürgen-Christian Krieg,Jürgen-Christian Krieg +6 more
TL;DR: Failure to find any evidence suggesting an analgesic action of CRH or of the subsequent hormones of the HPA system was obtained despite the fact that CRH produced clear neuroendocrine responses such as increases in the plasma concentration of beta-endorphin and cortisol.
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