Hellen Hiza
Ifakara Health Institute
20 Papers
2 Citations
Hellen Hiza is an academic researcher from Ifakara Health Institute. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 4, co-authored 11 publications. Previous affiliations of Hellen Hiza include Swiss Tropical and Public Health Institute & University of Basel.
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Papers
Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim
Fabrizio Menardo,Fabrizio Menardo,Liliana K. Rutaihwa,Liliana K. Rutaihwa,Michaela Zwyer,Michaela Zwyer,Sonia Borrell,Sonia Borrell,Iñaki Comas,Emilyn Costa Conceição,Emilyn Costa Conceição,Mireia Coscolla,Helen Cox,Moses Joloba,Horng-Yunn Dou,Julia Feldmann,Julia Feldmann,Lukas Fenner,Lukas Fenner,Lukas Fenner,Janet A. M. Fyfe,Qian Gao,Darío García de Viedma,Alberto L. García-Basteiro,Sebastian M. Gygli,Sebastian M. Gygli,Jerry Hella,Jerry Hella,Jerry Hella,Hellen Hiza,Hellen Hiza,Levan Jugheli,Levan Jugheli,Lujeko Kamwela,Lujeko Kamwela,Lujeko Kamwela,Midori Kato-Maeda,Qingyun Liu,Serej D. Ley,Serej D. Ley,Serej D. Ley,Chloé Loiseau,Chloé Loiseau,Surakameth Mahasirimongkol,Surakameth Mahasirimongkol,Bijaya Malla,Bijaya Malla,Prasit Palittapongarnpim,Prasit Palittapongarnpim,Niaina Rakotosamimanana,Voahangy Rasolofo,Miriam Reinhard,Miriam Reinhard,Klaus Reither,Klaus Reither,Mohamed Sasamalo,Mohamed Sasamalo,Mohamed Sasamalo,Rafael Silva Duarte,Christophe Sola,Christophe Sola,Philip Noel Suffys,Karla Valéria Batista Lima,Dorothy Yeboah-Manu,Christian Beisel,Daniela Brites,Daniela Brites,Sebastien Gagneux,Sebastien Gagneux +68 more
TL;DR: In this paper, the authors analyzed 2,938 L1 and 2,030 L3 whole genome sequences originating from 69 countries and reconstructed the evolutionary history of these two lineages and identified genes under positive selection.
Preservation of Sputum Samples with Cetylpyridinium Chloride (CPC) for Tuberculosis Cultures and Xpert MTB/RIF in a Low-income Country.
Hellen Hiza,Basra Doulla,Mohamed Sasamalo,Mohamed Sasamalo,Mohamed Sasamalo,Jerry Hella,Jerry Hella,Jerry Hella,Lujeko Kamwela,Francis Mhimbira,Francis Mhimbira,Francis Mhimbira,Klaus Reither,Klaus Reither,Klaus Reither,Sebastien Gagneux,Sebastien Gagneux,Levan Jugheli,Levan Jugheli,Levan Jugheli,Lukas Fenner +20 more
TL;DR: CPC increases culture yield, decreases the proportion of contamination, and does not alter the performance of Xpert MTB/RIF.
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Prevalence and clinical significance of respiratory viruses and bacteria detected in tuberculosis patients compared to household contact controls in Tanzania: a cohort study.
Francis Mhimbira,Francis Mhimbira,Francis Mhimbira,Hellen Hiza,Emmanuel Mbuba,Jerry Hella,Jerry Hella,Jerry Hella,Lujeko Kamwela,Mohamed Sasamalo,M. Ticlla,Khadija Said,Khadija Said,Khadija Said,Grace Mhalu,Grace Mhalu,Grace Mhalu,Magreth Chiryamkubi,Christian Schindler,Klaus Reither,Sebastien Gagneux,Lukas Fenner +21 more
TL;DR: Respiratory viruses are common for both TB patients and household controls and may present with more severe TB disease, particularly when they are co-infected with both bacteria and viruses.
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Case–control diagnostic accuracy study of a non-sputum CD38-based TAM-TB test from a single milliliter of blood
Hellen Hiza,Hellen Hiza,Hellen Hiza,Jerry Hella,Jerry Hella,Jerry Hella,Ainhoa Arbués,Ainhoa Arbués,Beatrice Magani,Beatrice Magani,Beatrice Magani,Mohamed Sasamalo,Mohamed Sasamalo,Mohamed Sasamalo,Sebastien Gagneux,Sebastien Gagneux,Klaus Reither,Klaus Reither,Damien Portevin,Damien Portevin +19 more
TL;DR: Starting from one millilitre of fresh blood and being not influenced by HIV status, TAM-TB assay format and performance appears closely compatible with the optimal TPP accuracy criteria defined by WHO for a non-sputum confirmatory TB test.
Boosting effect of IL-7 in interferon gamma release assays to diagnose Mycobacterium tuberculosis infection.
Hellen Hiza,Lukas Fenner,Jerry Hella,Jerry Hella,Jerry Hella,Davis Kuchaka,Mohamed Sasamalo,Mohamed Sasamalo,Mohamed Sasamalo,Thomas Blauenfeldt,Gibson S. Kibiki,Reginald A. Kavishe,Francis Apolinary Mhimbira,Morten Ruhwald +13 more
TL;DR: In TB cases addition of IL-7 in IGRA tubes augments IFN-γ but not IP-10 release, and seems to lower the response in controls, which needs to be confirmed in larger studies in high and low TB incidence countries.
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