Hélène Martin
French Institute of Health and Medical Research
5 Papers
90 Citations
Hélène Martin is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 4, co-authored 5 publications.
Chat about Author
Papers
Human Cytomegalovirus Induces Drug Resistance and Alteration of Programmed Cell Death by Accumulation of ΔN-p73α *
Sophie Allart,Hélène Martin,Claire Détraves,Jérôme Terrasson,Daniel Caput,Christian Davrinche +5 more
TL;DR: It is demonstrated that HCMV-mediated inhibition of apoptosis only occurs in p73-expressing cells, providing the first molecular basis for HCMVs-associated abnormal embryonic development and neurological defects in newborns.
47
Age-Related Differences in Sensitivity of Peripheral Blood Monocytes to Lipopolysaccharide and Staphylococcus Aureus Toxin B in Atopic Dermatitis
Marie Mandron,Marie-Françoise Ariès,Franck Boralevi,Franck Boralevi,Hélène Martin,Marie Charveron,Alain Taieb,Christian Davrinche +7 more
TL;DR: The data support the notion that monitoring sensitivity of monocytes to bacterial toxins could prove useful to assess disease progression and prognosis in AD and suggest new hypotheses to explain disease regression are suggested.
28
Dendritic cell-induced apoptosis of human cytomegalovirus-infected fibroblasts promotes cross-presentation of pp65 to CD8+ T cells.
Marie Mandron,Hélène Martin,Béatrice Bonjean,Jacqueline Lulé,Eric Tartour,Christian Davrinche +5 more
TL;DR: It is demonstrated that changes in the ratio of c-FLIP to FLICE contributed to early sensitivity of HCMV-infected MRC5 fibroblasts to tumour necrosis factor alpha (TNF-alpha), providing an innate response to infection.
18
Interplay between human cytomegalovirus and dendritic cells in T cell activation
TL;DR: It is suggested that uninfected dendritic cells could acquire HCMV-antigens derived from input virus or neosynthesis, either in soluble forms or in association with infected dead cells resulting from death-ligand-mediated apoptosis and necrosis, providing an explanation for shape and size of the memory compartment.
Activation of PPARγ by human CMV for de novo replication impairs invasiveness of cytotrophoblast from early placenta
Benjamin Rauwel,Bernard Mariamé,Hélène Martin,Danièle Evain-Brion,Thierry Fournier,Christian Davrinche +5 more
TL;DR: It is hypothesized that HCMV could impair placentation through activation of PPARγ, which is known to play a pivotal role in controlling human trophoblast invasion.