Helen Sutton
Manchester Metropolitan University
6 Papers
109 Citations
Helen Sutton is an academic researcher from Manchester Metropolitan University. The author has contributed to research in topics: Time-of-flight mass spectrometry & Matrix (chemical analysis). The author has an hindex of 4, co-authored 6 publications.
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Papers
Compilation of a MALDI-TOF mass spectral database for the rapid screening and characterisation of bacteria implicated in human infectious diseases.
Carrina J. Keys,Diane Dare,Helen Sutton,Graeme Wells,Martin Lunt,Therese McKenna,Mark McDowall,Haroun N. Shah +7 more
TL;DR: The results to date show unequivocally that as the number of strains per species increased, so too did the success of species matching, and this provides a new dimension for the rapid and high throughput characterisation of human pathogens with potentially broad applications across the field of microbiology.
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Matrix-assisted laser desorption ionisation-time-of of-flight mass spectrometry of intact cells allows rapid identification of Burkholderia cepacia complex.
Elke Vanlaere,Kjell Sergeant,Peter Dawyndt,Wibke Kallow,Marcel Erhard,Helen Sutton,Diane Dare,Bart Devreese,Bart Samyn,Peter Vandamme +9 more
TL;DR: It is demonstrated that MALDI-TOF MS is a powerful approach for the rapid identification of Bcc bacteria.
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High throughput identification of clinical isolates of Staphylococcus aureus using MALDI-TOF-MS of intact cells.
Lakshani Rajakaruna,Gillian Hallas,Linda Molenaar,Diane Dare,Helen Sutton,Vesela Encheva,Renata Culak,Ingrid Innes,Graham Ball,Armine Sefton,Melvin Eydmann,Angela M. Kearns,Haroun N. Shah +12 more
TL;DR: MALDI-TOF-MS has the potential to perform high throughput identification of clinical isolates of S. aureus despite the inherent diversity of this species, but is only reproducible if variable parameters such as sample preparation, media, growth condition, etc. are standardised.
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Collimonas arenae sp. nov. and Collimonas pratensis sp. nov., isolated from (semi-)natural grassland soils.
Sachie Höppener-Ogawa,W.F. de Boer,Johan H. J. Leveau,J.A. Van Veen,E. De Brandt,Elke Vanlaere,Helen Sutton,Diane Dare,Peter Vandamme +8 more
TL;DR: Genomic fingerprinting, whole-cell protein electrophoresis, matrix-assisted laser desorption ionization time-of-flight mass spectrometry of intact cells and physiological characterization of isolates confirmed the existence of different strain clusters within the genus Collimonas.
Assessment of the stability of cell-surface components of microorganisms by MALDI-TOF-MS following preservation on lenticule discs.
Haroun N. Shah,Linda Molenaar,Lakshani Rajakaruna,Julie E. Russell,Diane Dare,Helen Sutton,Gillian Hallas +6 more
TL;DR: High degree of concordance between cells preserved by both methods suggest that the properties of cells preserved on lenticule disc are consistent with those archived by the traditional method of freeze-drying.
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