Lawsonia inermis L. is a much branched glabrous shrub or small tree, cultivated for its leaves although stem bark, roots, flowers and seeds have also been used in traditional medicine. The plant is reported to contain carbohydrates, proteins, flavonoids, tannins and phenolic compounds, alkaloids, terpenoids, quinones, coumarins, xanthones and fatty acids. The plant has been reported to have analgesic, hypoglycemic, hepatoprotective, immunostimulant, anti-inflammatory, antibacterial, antimicrobial, antifungal, antiviral, antiparasitic, antitrypanosomal, antidermatophytic, antioxidant, antifertility, tuberculostatic and anticancer properties. It is now considered as a valuable source of unique natural products for development of medicines against various diseases and also for the development of industrial products. This review gives a bird’s eye view mainly on the pharmacognostic characteristics, traditional uses, phytochemistry and pharmacological actions of the plant.

/pdf/lawsonia-inermis-linnaeus-a-phytopharmacological-review-4t56qdk1mw.pdf

Lawsonia inermis linnaeus: a phytopharmacological review

Complementary and alternative medicine use among Jordanian patients with diabetes.

Alpha-glucosidase inhibitory activity of fifteen Indian medicinal plants has been evaluated by in vitro enzyme assay. Methanol extracts of Cyperus rotundus (tubers), Plumbago zeylanica (root), Symplocos racemosa (bark), and Terminalia arjuna (bark) had displayed 100% inhibition with the IC 50 value of 3.98 µg/ml, 3.46 µg/ml, 8.16 µg/ml and 0.69 µg/ml, respectively. Bark extract of Terminalia arjuna is highly effective against alpha- glucosidase activity even at nanogram concentration. Plant parts of Piper retrofractum (stem), Zingiber officinale (rhizome), Acorus calamus (rhizome), Picrorhiza kurroa (rhizome), Marsdenia tenacissima (stem), Clerodendron serratum (root), and Rubia cordifolia (root) are not effective and they require high concentration to exhibit inhibition. Potential plants that show maximum inhibition at low concentration (<10 µg/ml) were subjected to kinetic analysis to determine the mode of inhibition of the enzyme. Cyperus rotundus, Symplocos racemosa and Terminalia arjuna exhibited uncompetitive inhibition and Plumbago zeylanica had displayed mixed inhibition to alpha-glucosidase enzyme activity. From the enzyme assay, we infer that Cyperus rotundus, Plumbago zeylanica, Symplocos racemosa and Terminalia arjuna contain potential alpha-glucosidase inhibitors that can be exploited for its use in the treatment of diabetes.

pdf/screening-of-fifteen-indian-ayurvedic-plants-for-alpha-58b648r0xy.pdf

Screening of fifteen indian ayurvedic plants for alpha-glucosidase inhibitory activity and enzyme kinetics

In India, indigenous remedies have been used in the treatment of diabetes mellitus since the time of Charaka and Sushruta. Plants have always been an exemplary source of drugs and many of the currently available drugs have been derived directly or indirectly from them. The ethnobotanical information reports that about 800 plants may possess anti-diabetic potential. Out of several Indian medicinal plants 33 plants were reviewed. The most effective antidiabetic Indian medicinal plants are Acacia arabica, Aegle marmelose, Agrimonia eupatoria, Allium cepa, Allium sativum, Aloe vera, Azadirachta indica, Benincasa hispida, Beta vulgaris, Caesalpinia bonducella, Citrullus colocynthis, Coccinia indica, Eucalyptus globules, Ficus bengalenesis, Gymnema sylvestre, Hibiscus rosasinesis, Ipomoea batatas, Jatropha curcus, Mangifera indica, Momordica charantia, Morus alba, Mucuna pruriens, Ocimum sanctum, Pterocarpus marsupium, Punica granatum, Syzigium cumini, Tinospora cordifolia, Trigonella foenum graecum. A wide array of plant derived active principles representing numerous chemical compounds has demonstrated activity consistent with their possible use in the treatment of diabetes.

Current status of Indian medicinal plants with antidiabetic potential: a review

/pdf/wound-healing-activity-of-cuttlefish-gelatin-gels-and-films-1j2hdztsww.pdf

Wound healing activity of cuttlefish gelatin gels and films enriched by henna (Lawsonia inermis) extract

Pakistan is rich in medicinally important plants and has ancient herbal treatment methods. Present work is based on the study of six indigenous plants Eugenia jambolana, Lawsonia inermis, Momordica charantia, Morus

/pdf/in-vitro-hypoglycemic-activity-of-methanolic-extract-of-some-35hvupg8jn.pdf

In vitro hypoglycemic activity of methanolic extract of some indigenous plants

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In vitro hypoglycemic activity of methanolic extract of some indigenous plants