Heather Stuart
University of British Columbia
23 Papers
204 Citations
Heather Stuart is an academic researcher from University of British Columbia. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 11 publications.
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Papers
Instituting surveillance guidelines and adverse outcomes in preeclampsia.
Jennifer Menzies,Laura A. Magee,Jing Li,Ying C. MacNab,Ruihua Yin,Heather Stuart,Brandon Baraty,Elaine Lam,Trevor D. Hamilton,Shoo K. Lee,Peter von Dadelszen +10 more
TL;DR: Standardized surveillance of women with preeclampsia was associated with reduced maternal risk, and guidelines to introduce standardized assessment and surveillance were introduced.
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Tumor Cell Pseudopodial Protrusions LOCALIZED SIGNALING DOMAINS COORDINATING CYTOSKELETON REMODELING, CELL ADHESION, GLYCOLYSIS, RNA TRANSLOCATION, AND PROTEIN TRANSLATION
Zongjian Jia,Laurence Barbier,Heather Stuart,Mohammad Amraei,Steven L. Pelech,James W. Dennis,Pavel Metalnikov,Paul O'Donnell,Ivan R. Nabi,Ivan R. Nabi +9 more
TL;DR: Rho/ROCK activation in epithelial tumor cells therefore regulates RNA translocation to a pseudopodial domain that contains proteins involved in signaling, cytoskeleton remodeling, cell adhesion, glycolysis, and protein translation and degradation.
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Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions.
Heather Stuart,Zongjian Jia,Anat Messenberg,Bharat H. Joshi,T. Michael Underhill,Hakima Moukhles,Ivan R. Nabi +6 more
TL;DR: It is shown that activated RhoA, but not Rac1, is enriched in pseudopodia of MSV-MDCK-INV tumor cells and that Rho, Rho kinase (ROCK), and myosin II regulate the microtubule-independent targeting of RNA to these tumor cell domains.
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Laparoscopic versus open resection in patients with locally advanced colon cancer.
TL;DR: The role of laparoscopic resection in locally advanced colon cancer (LACC) is controversial due to tumor size and the frequent need for multivisceral resection as discussed by the authors.
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Treatment of borderline resectable (BR) and locally advanced (LA) pancreatic cancer in the era of FOLFIRINOX and gemcitabine plus nab-paclitaxel: A multi-institutional study.
Kamran Idrees,Alexander A. Parikh,Lauren M. Postlewait,Sharon M. Weber,Clifford S. Cho,Ahmed Salem,Robert C.G. Martin,Charles R. Scoggins,Hong Jin Kim,Jacquelyn Carr,Heather Stuart,Brent T. Xia,Syed Moiz Ahmed,Daniel E. Abbott,Shishir K. Maithel,David A. Kooby,Nipun B. Merchant +16 more
TL;DR: This report describes the multi-institutional experience with NA treatment with FOLFIRINOX or Gem/nPac followed by surgical resection for Stage 4 pancreatic cancer patients at 7 high volume pancreas centers between 2011 and 2015.
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