189 Papers
1K Citations
He Li is an academic researcher from University of Cambridge. The author has contributed to research in topics: Computer science & Geology. The author has an hindex of 39, co-authored 165 publications. Previous affiliations of He Li include National Institutes of Health & Yangzhou University.
Chat about Author
Papers
Porphyry deposits and oxidized magmas
Weidong Sun,Ruifang Huang,He Li,Yongbin Hu,Chan-chan Zhang,Sai-Jun Sun,Lipeng Zhang,Xing Ding,Congying Li,Robert E. Zartman,Ming-Xing Ling +10 more
TL;DR: Porphyry deposits supply most of the world's Cu and Mo resources Over 90% of the porphyry mines are found at convergent margins, especially above active subduction zones, with much fewer occurrences at postcollisional or other tectonic settings Porphyry Cu-(Mo)−(Au) deposits are essentially magmatic-hydrothermal systems, which are generally initiated by injection of oxidized magmas saturated with metal-rich aqueous fluids, i.e., the parental magmas need to be water rich and oxidized with most
501
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
Haibo Zhou,Jinlin Su,Xinde Hu,Changyang Zhou,He Li,Zhaorong Chen,Qingquan Xiao,B. D. Wang,Wenyan Wu,Yidi Sun,Yingsi Zhou,Cheng Tang,Fei Liu,Linhan Wang,Canbin Feng,Mingzhe Liu,Sanlan Li,Yifeng Zhang,Hua-Tai Xu,Haishan Yao,Linyu Shi,Hui Yang +21 more
TL;DR: Glia-to-neuron conversion by CasRx-mediated Ptbp1 knockdown represents a promising in vivo genetic approach for treating a variety of disorders due to neuronal loss.
384
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice
Haibo Zhou,Junlai Liu,Junlai Liu,Changyang Zhou,Ni Gao,Zhiping Rao,He Li,Xinde Hu,Changlin Li,Xuan Yao,Xiaowen Shen,Yidi Sun,Yu Wei,Fei Liu,Wenqin Ying,Junming Zhang,Cheng Tang,Xu Zhang,Hua-Tai Xu,Linyu Shi,Leping Cheng,Pengyu Huang,Hui Yang +22 more
TL;DR: A transgenic mouse is generated using an improved dCas9 system that enables simultaneous and precise in vivo transcriptional activation of multiple genes and long noncoding RNAs in the nervous system and is able to use targeted activation of endogenous neurogenic genes in these transgenic mice to directly and efficiently convert astrocytes into functional neurons in vivo.
252
A record of spontaneous subduction initiation in the Izu–Bonin–Mariana arc
Richard J. Arculus,Osamu Ishizuka,Osamu Ishizuka,Kara Bogus,Michael Gurnis,Rosemary Hickey-Vargas,Mohammed Aljahdali,Alexandre N. Bandini-Maeder,Andrew P. Barth,Philipp A. Brandl,Philipp A. Brandl,Laureen Drab,Rodrigo do Monte Guerra,Morihisa Hamada,Fuqing Jiang,Kyoko Kanayama,Sev Kender,Sev Kender,Yuki Kusano,He Li,Lorne Loudin,Marco Maffione,Kathleen M. Marsaglia,Anders McCarthy,Sebastien Meffre,Antony Morris,M. Neuhaus,Ivan P. Savov,Clara Sena,Frank J. Tepley,Cees van der Land,Gene Yogodzinski,Zhaohui Zhang +32 more
TL;DR: In this paper, the authors analyse the geochemical characteristics of igneous basement rocks and overlying sediments, sampled from the Amami Sankaku Basin in the northwest Philippine Sea.
Reliability analysis of a floating offshore wind turbine using Bayesian Networks
TL;DR: The computed results in this paper are more conformity with statistical data for that the error of predicted failure rate of this study is 4.5%, which can be compared with that of 13% concluded by fault tree analysis.
195