Hasan Alghetaa
University of South Carolina
16 Papers
Hasan Alghetaa is an academic researcher from University of South Carolina. The author has contributed to research in topics: Medicine & ARDS. The author has an hindex of 8, co-authored 12 publications.
Chat about Author
Papers
Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome
TL;DR: In this article, the role of the microbiome in the attenuation of clinical signs of paralysis and inflammation caused by cannabinoids was investigated in patients with Multiple Sclerosis (MS) using 16S rRNA sequencing.
117
Resveratrol Attenuates Allergic Asthma and Associated Inflammation in the Lungs Through Regulation of miRNA-34a That Targets FoxP3 in Mice
Esraah Alharris,Hasan Alghetaa,Ratanesh Seth,Saurabh Chatterjee,Narendra P. Singh,Mitzi Nagarkatti,Prakash S. Nagarkatti +6 more
TL;DR: The current study suggests that resveratrol attenuates allergic asthma by downregulating miR-34a that induces increased expression of FOXP3, a master regulator of Treg development and functions.
89
AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes.
Wurood Hantoosh Neamah,Narendra P. Singh,Hasan Alghetaa,Osama A Abdulla,Saurabh Chatterjee,Philip B. Busbee,Mitzi Nagarkatti,Prakash S. Nagarkatti +7 more
TL;DR: It is demonstrated that activation of AhR in naive mice triggers robust mobilization of MDSCs through induction of chemokines and their receptors and MDSC activation through regulation of miRNA expression.
79
The Ability of Resveratrol to Attenuate Ovalbumin-Mediated Allergic Asthma Is Associated With Changes in Microbiota Involving the Gut-Lung Axis, Enhanced Barrier Function and Decreased Inflammation in the Lungs
Esraah Alharris,Amira Mohammed,Hasan Alghetaa,Juhua Zhou,Mitzi Nagarkatti,Prakash S. Nagarkatti +5 more
TL;DR: It is found that Resveratrol can attenuate allergic asthma with significant improvements in pulmonary functions in OVA-exposed mice when tested using plethysmography for frequency, mean volume, specific airway resistance, and delay time.
47
Δ9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression.
Amira Mohammed,Hasan Alghetaa,Kathryn Miranda,Kiesha Wilson,Narendra P. Singh,Guoshuai Cai,Nagireddy Putluri,Prakash S. Nagarkatti,Mitzi Nagarkatti +8 more
TL;DR: It is suggested that the activation of cannabinoid receptors may serve as a therapeutic modality to treat ARDS associated with coronavirus-induced disease (COVID-19).
45