Harsha Mahabaleshwar
University of Münster
10 Papers
51 Citations
Harsha Mahabaleshwar is an academic researcher from University of Münster. The author has contributed to research in topics: Cell migration & Biology. The author has an hindex of 7, co-authored 7 publications.
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Papers
β-arrestin control of late endosomal sorting facilitates decoy receptor function and chemokine gradient formation
TL;DR: A novel role for β-arrestins is identified in controlling the intracellular trafficking of Cxcr7, which controls the level of the chemokine in the tissue and allows responding cells to discriminate between alternative migration targets in vivo.
The role of CXCR7 in regulating primordial germ cell migration
Harsha Mahabaleshwar,Bijan Boldajipour,Erez Raz +2 more
- 01 Jan 2008
TL;DR: A model according to which CXCR4b translates the polarized distribution of SDF-1 into directed PGC migration, while CX CR7 acts as a high-affinity decoy receptor and facilitates the migration of PGCs by shaping the distribution of the chemokine in the environment is discussed.
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Echolocation-like model of directed cell migration within growing tissues
TL;DR: It is shown that cells can take advantage of an echolocation-like process, whereby they induce a response from the tissue boundary, and this simple system may be applicable to fibroblast migration in the fin.
BMP signalling attenuates intercellular adhesion to drive mesenchyme migration during fin fold morphogenesis
Bitan Saha,Harsha Mahabaleshwar,Charmaine Ho Min,Leslie Boon Haw Leong,Levene Wenqian Chua,Samuel Kwok,Tom J. Carney +6 more
TL;DR: BMP signalling regulates mesenchyme migration during fin fold morphogenesis in zebrafish by attenuating intercellular adhesion, promoting cell migration and elongation, and altering N-cadherin dynamics, independently of sphingosine-1-phosphate signalling.
A median fin derived from the lateral plate mesoderm and the origin of paired fins
Keh-Weei Tzung,Robert L. Lalonde,Karin D. Prummel,Harsha Mahabaleshwar,Hannah R. Moran,Jan Stundl,Amanda N. Cass,Yao Le,Robert W. Lea,Karel Dorey,Eline Constance Brombacher,William B. White,Henry Roehl,Frank J. Tulenko,Christoph Winkler,Peter D. Currie,Enrique Amaya,Marcus C. Davis,Marianne E. Bronner,Christian Mosimann,Thomas J. Carney +20 more
TL;DR: In this article , it was shown that the larval zebrafish unpaired pre-anal fin fold (PAFF) is derived from the LPM and thus may represent a developmental intermediate between median and paired fin.