Harrison Wang
University of California, San Diego
3 Papers
2 Citations
Harrison Wang is an academic researcher from University of California, San Diego. The author has contributed to research in topics: RNA splicing & RNA. The author has an hindex of 2, co-authored 3 publications.
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Papers
Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9
Ranjan Batra,David A. Nelles,Elaine Pirie,Steven M. Blue,Ryan J. Marina,Harrison Wang,Isaac A. Chaim,James D. Thomas,Nigel Zhang,Vu T. Nguyen,Stefan Aigner,Sebastian Markmiller,Guangbin Xia,Kevin D. Corbett,Kevin D. Corbett,Maurice S. Swanson,Gene W. Yeo +16 more
TL;DR: RNA-targeting Cas9 (RCas9) reverses hallmark features of disease including elimination of RNA foci among all conditions studied, reduction of polyglutamine protein products, relocalization of repeat-bound proteins to resemble healthy controls, and efficient reversal of DM1-associated splicing abnormalities in patient myotubes.
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Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System
Fernando J. Martinez,Gabriel A. Pratt,Eric L. Van Nostrand,Ranjan Batra,Stephanie C. Huelga,Katannya Kapeli,Katannya Kapeli,Peter Freese,Seung J. Chun,Karen Ling,Chelsea Gelboin-Burkhart,Layla Fijany,Harrison Wang,Julia K. Nussbacher,Sara Broski,Hong Joo Kim,Rea M. Lardelli,Balaji Sundararaman,John Paul Donohue,Ashkan Javaherian,Jens Lykke-Andersen,Steven Finkbeiner,C. Frank Bennett,Manuel Ares,Christopher B. Burge,J. Paul Taylor,Frank Rigo,Gene W. Yeo +27 more
TL;DR: The findings provide a cellular resource and reveal RNA networks relevant to neurodegeneration, regulated by normal and mutant hnRNP A2/B1.
166
Active extravasation of gadolinium-based contrast agent into the subdural space following lumbar puncture
TL;DR: The first reported case of active extravasation of gadolinium-based contrast agent in the spine is reported, following multiple lumbar puncture attempts with cauda equina syndrome.
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