BioMEMS/NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.

Integrated biosensor and simulation system for diagnosis and therapy

An information management system and method is provided for integrating structured and unstructured data using an ontological approach, and further comprises processes for creating, validating, augmenting, and combining ontologies for life science informatics and other disciplines.

Ontology-based information management system and method

Described herein are genes whose expression are up-regulated or down-regulated in specific cancers. Related methods and compositions that can be used for diagnosis and treatment of those cancers are disclosed. Also described herein are methods that can be used to identify modulators of selected cancers.

Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer

A system and method is disclosed for integrating and accessing multiple data sources within a data warehouse architecture. The metadata formed by the present method provide a way to declaratively present domain specific knowledge, obtained by analyzing data sources, in a consistent and useable way. Four types of information are represented by the metadata: abstract concepts, databases, transformations and mappings. A mediator generator automatically generates data management computer code based on the metadata. The resulting code defines a translation library and a mediator class. The translation library provides a data representation for domain specific knowledge represented in a data warehouse, including “get” and “set” methods for attributes that call transformation methods and derive a value of an attribute if it is missing. The mediator class defines methods that take “distinguished” high-level objects as input and traverse their data structures and enter information into the data warehouse.

System and method for integrating and accessing multiple data sources within a data warehouse architecture

Computer based systems, methods, software and databases are presented in which correlations between web item preferences, behaviors and pangenetic (genetic and epigenetic) attributes of individuals are used for pangenetic based user behavior prediction in which predictions of a user's online behavior can be generated based on the user's pangenetic makeup. Data masking can be used to maintain privacy of sensitive portions of the pangenetic data.

Pangenetic web user behavior prediction system

A computer system stores biomolecular data in a database in a memory. The biomolecular database has a set of entities. Each entity stores attributes for a plurality of entries. At least one attribute is stored in an array. Data associated with an entry is stored at a location in the array. An entity offset designates the location of the data in the array. The same entity offset value is used to access data associated with a particular entry for all attributes within the entity.

System and method for a precompiled database for biomolecular sequence information

Disclosed is a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to association with one or more projects for obtaining full-length biomolecular sequences from shorter sequences The relational database has sequence records containing information identifying one or more projects to which each of the sequence records belong Each project groups together one or more biomolecular sequences generated during work to obtain a full-length gene sequence from a shorter sequence The computer system has a user interface allowing a user to selectively view information regarding one or more projects The relational database also provides interfaces and methods for accessing and manipulating and analyzing project-based information

Project-based full-length biomolecular sequence database

Disclosed is a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to association with one or more projects for obtaining full-length biomolecular sequences from shorter sequences. The relational database has sequence records containing information identifying one or more projects to which each of the sequence records belong. Each project groups together one or more biomolecular sequences generated during work to obtain a full-length gene sequence from a shorter sequence. The computer system has a user interface allowing a user to selectively view information regarding one or more projects. The relational database also provides interfaces and methods for accessing and manipulating and analyzing project-based information.

Project-based full-length biomolecular sequence database with expression categories

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System and method for a precompiled database for biomolecular sequence information

Project-based full-length biomolecular sequence database

Project-based full-length biomolecular sequence database with expression categories