Harold F. Dvorak
Beth Israel Deaconess Medical Center
351 Papers
7.3K Citations
Harold F. Dvorak is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Angiogenesis & Vascular endothelial growth factor. The author has an hindex of 117, co-authored 351 publications. Previous affiliations of Harold F. Dvorak include Harvard University & Benaroya Research Institute.
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Papers
Ultrastructural Criteria for Identification of Mast Cells and Basophils in Humans, Guinea Pigs, and Mice1–4
TL;DR: Variations in basophil and mast cell ultrastructure that reflect the cells' functional activity or stage of maturation are described, which promise to rapidly increase the understanding of the roles of basophils and mast cells in health and disease.
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Metallo-enzymes Released from Escherichia coli by Osmotic Shock II. EVIDENCE THAT 5'-NUCLEOTIDASE AND CYCLIC PHOSPHODIESTERASE ARE ZINC METALLOENZYMES
Harold F. Dvorak,Leon A. Heppel +1 more
TL;DR: It is suggested that cyclic phosphodiesterase and 5'-nucleotidase are metalloproteins and possibly zinc metalloenzymes.
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Pathogenesis of Desmoplasia. I. Immunofluorescence Identification and Localization of Some Structural Proteins of Line 1 and Line 10 Guinea Pig Tumors and of Healing Wounds 1,2
TL;DR: The structural proteins of the scirrhous line 1 and the medullary line 10 bile duct carcinomas, both syngeneic in strain 2 Sewall-Wright inbred guinea pigs, were studied and suggest that tumor desmoplasia is analogous to wound healing.
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A cloned cell with NK function resembles basophils by ultrastructure and expresses IgE receptors.
Stephen J. Galli,Stephen J. Galli,Ann M. Dvorak,Ann M. Dvorak,Teruko Ishizaka,Gary J. Nabel,Harout Der Simonian,Harvey Cantor,Harold F. Dvorak,Harold F. Dvorak +9 more
TL;DR: These findings indicate that cells sharing morphological and biochemical features of basophilic granulocytes can mediate NK lysis, and suggest that NK cell activity resides in a small proportion of normal mouse spleen cells that have been difficult to characterize completely.
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•Journal Article
Fibrin deposits in Hodgkin's disease.
TL;DR: The pathogenesis and possible significance of fibrin deposition in Hodgkin's disease are related to earlier observations of activation of the coagulation system on neoplasia and cell-mediated immunity and to the possible role of fibin, fibronectin, and their breakdown products in angiogenesis and fibroplasia.
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